Should PNPO Deficiency Be Treated In Utero? Clinical Findings From Prenatal Pyridoxine Therapy
ABSTRACT Pyridox(am)ine‐5′‐phosphate oxidase (PNPO) deficiency is characterized by early‐onset epileptic encephalopathy refractory to standard antiseizure medications. It is caused by variants in the PNPO gene, resulting in deficient PNPO enzyme activity, which normally converts pyridoxine‐5′‐phosphate and pyridoxamine‐5′‐phosphate (two vitamers of ...
Chloé de Puyraimond +10 more
wiley +1 more source
Testicular shear wave elastography in varicocele: measurement strategy and clinical application. [PDF]
Zhang L +5 more
europepmc +1 more source
Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault +9 more
wiley +1 more source
Artificial intelligence and elastography in diagnostic work-up of thyroid nodules: a systematic review and meta-analysis. [PDF]
Li X +9 more
europepmc +1 more source
ABSTRACT Purpose To design 3D radial spiral phyllotaxis trajectories aimed at removing phase inconsistencies, improving image quality, and enhancing parametric mapping accuracy by acquiring nearly opposing spokes starting from both hemispheres in 3D radial k‐space. Methods Two 3D radial trajectories, pole‐to‐pole and continuous spiral phyllotaxis, were
Eva S. Peper +12 more
wiley +1 more source
Comments on "Feasibility of Viscosity Imaging and Shear Wave Elastography for Diagnosing Diabetic Peripheral Neuropathy". [PDF]
Zhou Y, Li M, Cai M.
europepmc +1 more source
Exploring the Role of Vascular Factors and Tissue Properties in Pulsatile Brain Deformation
This study combined strain tensor imaging (STI), intrinsic magnetic resonance elastography (iMRE), and atlas‐based regional metrics to explore physiological drivers of cardiac‐induced brain strain. Volumetric strain was mainly associated with vascular factors such as cerebral blood volume and pulse pressure, whereas octahedral shear strain correlated ...
Marius Burman Ingeberg +3 more
wiley +1 more source
ABSTRACT Background and Aims Detecting gastroesophageal varices with a high risk of bleeding (HRV) in children with biliary atresia requires endoscopies from an early age to apply primary prophylaxis of bleeding. However, repeated endoscopies are invasive and costly.
Virginie Lambert +9 more
wiley +1 more source
Shear wave elastography combined with fine-needle aspiration biopsy in the diagnosis of China Thyroid Imaging Reporting and Data System category 4 thyroid nodules. [PDF]
Xu RY +6 more
europepmc +1 more source

