Results 191 to 200 of about 70,999 (292)

Should PNPO Deficiency Be Treated In Utero? Clinical Findings From Prenatal Pyridoxine Therapy

open access: yesJIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT Pyridox(am)ine‐5′‐phosphate oxidase (PNPO) deficiency is characterized by early‐onset epileptic encephalopathy refractory to standard antiseizure medications. It is caused by variants in the PNPO gene, resulting in deficient PNPO enzyme activity, which normally converts pyridoxine‐5′‐phosphate and pyridoxamine‐5′‐phosphate (two vitamers of ...
Chloé de Puyraimond   +10 more
wiley   +1 more source

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1069-1082, May 2026.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault   +9 more
wiley   +1 more source

Pole‐To‐Pole 3D Radial Trajectory Designs Improve Image Quality and Quantitative Parametric Mapping in the Brain and Heart

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2627-2643, May 2026.
ABSTRACT Purpose To design 3D radial spiral phyllotaxis trajectories aimed at removing phase inconsistencies, improving image quality, and enhancing parametric mapping accuracy by acquiring nearly opposing spokes starting from both hemispheres in 3D radial k‐space. Methods Two 3D radial trajectories, pole‐to‐pole and continuous spiral phyllotaxis, were
Eva S. Peper   +12 more
wiley   +1 more source

Exploring the Role of Vascular Factors and Tissue Properties in Pulsatile Brain Deformation

open access: yesNMR in Biomedicine, Volume 39, Issue 5, May 2026.
This study combined strain tensor imaging (STI), intrinsic magnetic resonance elastography (iMRE), and atlas‐based regional metrics to explore physiological drivers of cardiac‐induced brain strain. Volumetric strain was mainly associated with vascular factors such as cerebral blood volume and pulse pressure, whereas octahedral shear strain correlated ...
Marius Burman Ingeberg   +3 more
wiley   +1 more source

Elastography

open access: yes, 2013
Ayush Goel   +2 more
openaire   +1 more source

Echocardiography, Bile Acids and Spleen Stiffness to Rule Out High‐Risk Varices in Children With Biliary Atresia

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Detecting gastroesophageal varices with a high risk of bleeding (HRV) in children with biliary atresia requires endoscopies from an early age to apply primary prophylaxis of bleeding. However, repeated endoscopies are invasive and costly.
Virginie Lambert   +9 more
wiley   +1 more source

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