Results 1 to 10 of about 342,502 (309)

Hydrogen Peroxide Is an Endothelium-Derived Hyperpolarizing Factor in Animals and Humans

Journal of Pharmacological Sciences, 2003
Vascular endothelium plays an important role in maintaining vascular homeostasis by synthesizing and releasing several vasodilating factors, such as prostacyclin, nitric oxide (NO), and a yet unidentified endothelium-derived hyperpolarizing factor (EDHF).
Matoba Tetsuya, Hiroaki Shimokawa
doaj   +1 more source

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

Nature Communications, 2019
HSCs emerge from haemogenic endothelium (HE) in the dorsal aorta but whether these tissues share a common lineage is unclear. Here, the authors use a zebrafish runx1 reporter to show that HE maintains an arterial gene expression profile in the absence of
Florian Bonkhofer, Rossella Rispoli, Philip Pinheiro, Monika Krecsmarik, Janina Schneider-Swales, Ingrid Ho Ching Tsang, Marella de Bruijn, Rui Monteiro, Tessa Peterkin, Roger Patient   +9 more
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Age-Related Disappearance of the Inhibitory Effect of Vascular Endothelium on Agonist-Induced Vasoconstriction in Rat Mesenteric Vascular Beds

Journal of Pharmacological Sciences, 2009
We previously reported that endothelium-derived hyperpolarizing factor (EDHF)– mediated response time-dependently suppressed methoxamine-induced vasoconstriction in mesenteric vascular beds isolated from 8-week-old rats.
Xin Jin, Yukiko Satoh-Otonashi, Yoshito Zamami, Narumi Hobara, Toshihiro Koyama, Pengyuan Sun, Simin Li, Yoshihisa Kitamura, Hiromu Kawasaki   +8 more
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Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues.

PLoS ONE, 2016
The selective entry of nanoparticles into target tissues is the key factor which determines their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which have tissue-specific properties.
Radka Gromnicova, Mehmet Kaya, Ignacio A Romero, Phil Williams, Simon Satchell, Basil Sharrack, David Male   +6 more
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The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches

Advances in Virology, 2012
American hantaviruses cause a highly lethal acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). Hantaviruses nonlytically infect endothelial cells and cause dramatic changes in barrier functions of the endothelium without disrupting the ...
Irina Gavrilovskaya, Elena Gorbunova, Valery Matthys, Nadine Dalrymple, Erich Mackow   +4 more
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The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung

Particle and Fibre Toxicology, 2005
Background Translocation of ultrafine particles (UFP) into the blood that returns from the lungs to the heart has been forwarded as a mechanism for particle-induced cardiovascular effects.
Takenaka Shinji, Seitz Jürgen, Semmler Manuela, Bagate Karim, Borm Paul JA, Meiring James J, Kreyling Wolfgang G   +6 more
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Endothelial connexins in vascular function

Vascular Biology, 2019
Gap junctions are essential for intercellular crosstalk in blood and lymphatic vasculature. These clusters of intercellular channels ensure direct communication among endothelial cells and between endothelial and smooth muscle cells, and the ...
Aurélie Hautefort, Anna Pfenniger, Brenda R Kwak   +2 more
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Heart Failure With Preserved Ejection Fraction: A Review of Cardiac and Noncardiac Pathophysiology

Frontiers in Physiology, 2019
Heart failure with preserved ejection fraction (HFpEF) is one of the largest unmet clinical needs in 21st-century cardiology. It is a complex disorder resulting from the influence of several comorbidities on the endothelium. A derangement in nitric oxide
Andreas B. Gevaert, Andreas B. Gevaert, Andreas B. Gevaert, Jente R. A. Boen, Jente R. A. Boen, Vincent F. Segers, Vincent F. Segers, Emeline M. Van Craenenbroeck, Emeline M. Van Craenenbroeck, Emeline M. Van Craenenbroeck   +9 more
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Linolenic Acid Attenuates the Vasodilation Induced by Acetylcholine in Isolated Rat Aortae

Dose-Response, 2019
This study aims to examine the effect of linolenic acid on the vasodilation or vasoconstriction induced by acetylcholine and bupivacaine in isolated rat aortae and its underlying mechanism.
Soo Hee Lee, Seong-Ho Ok, Ji-Yoon Kim, Raghavendra Baregundi Subbarao, Sung Il Bae, Yeran Hwang, Kyeong-Eon Park, Jong Won Kim, Ju-Tae Sohn   +8 more
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Comparison of rebubbling rate between preloaded endothelium-in and preloaded no-touch endothelium-out Descemet membrane endothelial keratoplasty transplantation

BMC Ophthalmology
Background To compare the difference in rebubbling rates between patients undergoing Descemet membrane endothelial keratoplasty (DMEK) with endothelium-in using a standard IOL cartridge and those with endothelium-out DMEK utilizing a no-touch technique ...
Martin Kronschläger, Alessandro Ruzza, Johannes Zeilinger, Andreas Schlatter, Manuel Ruiss, Oliver Findl   +5 more
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