Results 21 to 30 of about 342,502 (309)

Reproducibility and research integrity: the role of scientists and institutions

BMC Research Notes, 2021
Reproducibility and research integrity are essential tenets of every scientific study and discovery. They serve as proof that an established and documented work can be verified, repeated, and reproduced.
Patrick Diaba-Nuhoho, Michael Amponsah-Offeh   +1 more
doaj   +1 more source

Physiology of the endothelium [PDF]

British Journal of Anaesthesia, 2004
In the past, the endothelium was considered to be inert, described as a 'layer of nucleated cellophane', with only non-reactive barrier properties, such as presentation of a non-thrombogenic surface for blood flow and guarding against pro-inflammatory insults.
H F, Galley, N R, Webster
openaire   +2 more sources

Cross-Talk of NADPH Oxidases and Inflammation in Obesity

Antioxidants, 2023
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz, Heike Brendel, Patrick Diaba-Nuhoho, Rusan Catar, Nikolaos Perakakis, Christian Wolfrum, Stefan R. Bornstein   +6 more
doaj   +1 more source

Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide [PDF]

, 2004
Background: Ischemia/reperfusion (I/R) injury complicates myocardial infarction and stroke by exacerbating tissue damage and increasing risk of mortality.
Ramona Scotl, Hobbs, Adrian, Ahluwalia, Amrita, Foster, Paul, Hobbs, A., Phd Amrita Ahluwalia, Foster, P., Adrian Hobbs, Phd Paul Foster, Scotland, R., Prescott, Craig, Scotland, Ramona, Ahluwalia, A., Phd Craig Prescott, Natriuretic Peptide, Prescott, C.   +15 more
core   +1 more source

Oxidative Stress, Antioxidants and Hypertension

Antioxidants, 2023
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to global public health. Despite the availability of many antihypertensive medications, several hypertensive individuals are resistant to standard treatments, and
Michael Amponsah-Offeh, Patrick Diaba-Nuhoho, Stephan Speier, Henning Morawietz   +3 more
doaj   +1 more source

ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay, Paul R. Coleman, Ann Formaz‐Preston, Ka Ka Ting, Ben Roediger, Wolfgang Weninger, Martin A. Schwartz, Mathew A. Vadas, Jennifer R. Gamble   +8 more
doaj   +1 more source

“Endothelium-Out” and “Endothelium-In” Descemet Membrane Endothelial Keratoplasty (DMEK) Graft Insertion Techniques: A Systematic Review With Meta-Analysis

Frontiers in Medicine, 2022
BackgroundWe evaluated the visual outcomes and complications of “endothelium-out” and “endothelium-in” Descemet membrane endothelial keratoplasty (DMEK) graft insertion techniques.Materials and MethodsElectronic searches were conducted in CENTRAL ...
Hon Shing Ong, Hon Shing Ong, Hon Shing Ong, Hla M. Htoon, Hla M. Htoon, Marcus Ang, Marcus Ang, Marcus Ang, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta   +11 more
doaj   +1 more source

The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b

Molecular Therapy: Nucleic Acids, 2016
The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li, Yang Zhao, Ying Lu, William Ritchie, Georges Grau, Mathew A Vadas, Jennifer R Gamble   +6 more
doaj   +1 more source

Mercaptoethylguanidine is a selective inducible nitric oxide synthase inhibitor on pulmonary artery

Tungs’ Medical Journal, 2023
Background: Nitric oxide (NO) is a colorless and odorless toxic gas and a short-acting physiological vasodilator. NO is produced by nitric oxide synthase (NOS).
Xian-He Shyanher Wang
doaj   +1 more source

The artificial endothelium [PDF]

Organogenesis, 2011
As the world of critical care medicine advances, extracorporeal therapies (ECC) have become commonplace in the management of the high risk intensive care patient. ECC encompasses a wide variety of technologies from hemodialysis, continuous renal replacement therapy (CRRT) and plasmapheresis, to cardiopulmonary bypass (CPB), extracorporeal life support (
Melissa M, Reynolds, Gail M, Annich
openaire   +2 more sources