Results 21 to 30 of about 261,152 (266)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay +8 more
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Frontiers in Medicine, 2022 BackgroundWe evaluated the visual outcomes and complications of “endothelium-out” and “endothelium-in” Descemet membrane endothelial keratoplasty (DMEK) graft insertion techniques.Materials and MethodsElectronic searches were conducted in CENTRAL ...
Hon Shing Ong +11 more
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Molecular Therapy: Nucleic Acids, 2016 The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li +6 more
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Mercaptoethylguanidine is a selective inducible nitric oxide synthase inhibitor on pulmonary artery
Tungs’ Medical Journal, 2023 Background: Nitric oxide (NO) is a colorless and odorless toxic gas and a short-acting physiological vasodilator. NO is produced by nitric oxide synthase (NOS).
Xian-He Shyanher Wang
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Physiology of the endothelium [PDF]
British Journal of Anaesthesia, 2004 In the past, the endothelium was considered to be inert, described as a 'layer of nucleated cellophane', with only non-reactive barrier properties, such as presentation of a non-thrombogenic surface for blood flow and guarding against pro-inflammatory insults.
H F, Galley, N R, Webster
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Redox Biology, 2017 Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe +6 more
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The artificial endothelium [PDF]
Organogenesis, 2011 As the world of critical care medicine advances, extracorporeal therapies (ECC) have become commonplace in the management of the high risk intensive care patient. ECC encompasses a wide variety of technologies from hemodialysis, continuous renal replacement therapy (CRRT) and plasmapheresis, to cardiopulmonary bypass (CPB), extracorporeal life support (
Melissa M, Reynolds, Gail M, Annich
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The Endothelium in Acromegaly [PDF]
Frontiers in Endocrinology, 2019 Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, although recent studies have shown a reduction in the ...
Maffei, Pietro +4 more
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Neurobiology of Disease, 2012 In industrialized countries, cerebral palsy affects 2.5‰ of preterm and term infants. At a neurochemical level, the massive release of glutamate constitutes a major process leading to excitotoxicity and neonatal brain lesions. Previous studies, conducted
Faiza El Ghazi +13 more
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