Results 41 to 50 of about 313,061 (314)

Lipids and the endothelium [PDF]

Cardiovascular Research, 1999
The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.
A M, Dart, J P, Chin-Dusting
openaire   +2 more sources

Effectiveness of a Novel Low‐Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb‐Threatening Ischemia: A Single‐Center Retrospective Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka, Takayasu Ohtake, Kei Ohmori, Chika Shibuya, Tomoki Tsukahara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Yusuke Tsukamoto, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi   +12 more
wiley   +1 more source

Endothelial cells modulate renin secretion from isolated mouse juxtaglomerular cells

, 1991
Utilizing cocultures of mouse renal juxtaglomerular cells with bovine microvascular endothelial cells, we have examined whether endothelial cells exert direct influence on renin secretion from renal juxtaglomerular cells.
Kaissling, Brigitte, Kurtz, Armin, Baier, Wolfgang, W Baier, R Busse, A Kurtz, Busse, Rudi, B Kaissling   +7 more
core   +1 more source

Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers [PDF]

, 2009
Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of CVD. However, Champagne wine has not been fully investigated for its cardioprotective potential. In order to assess whether acute and moderate
David Vauzour, George, Trevor, Sellier, C., George, Trevor W, George, Trevor W., Kennedy, Orla B., Spencer, Jeremy, Houseman, E.J., Lovegrove, Julie A, Houseman, Emily, Giulia Corona, Spencer, Jeremy P E, Garnotel, R., Kennedy, O.B., Kim G. Jackson, Spencer, Jeremy P. E., Jeremy P. E. Spencer, Julie A. Lovegrove, Vauzour, David, Corona, Giulia, Houseman, Emily J., Lovegrove, Julie A., Emily J. Houseman, Orla B. Kennedy, Houseman, Emily J, Garnotel, Roselyne, Vauzour, D., Corona, G., Jackson, K.G., Sellier, Christelle, Spencer, J.P.E., Lovegrove, J.A., Gillery, Philippe, Jackson, Kim G., Roselyne Garnotel, Trevor W. George, Lovegrove, Julie, Jackson, Kim G, George, T.W., Gillery, P., Christelle Sellier, Kennedy, Orla, Kennedy, Orla B   +42 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Vascular Function of Resistance Arteries Depends on NADPH Oxidase 4 and Is Exacerbated by Perivascular Adipose Tissue

Antioxidants
The NADPH oxidase NOX4 that releases H2O2 can mediate vasoprotective mechanisms under pathophysiological conditions in conductive arteries. However, the role of NOX4 in resistance arteries and in perivascular adipose tissue is not well understood.
Patrick Diaba-Nuhoho, Jennifer Mittag, Coy Brunssen, Henning Morawietz, Heike Brendel   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Nano-scale architecture of blood-brain barrier tight-junctions

eLife, 2021
Tight junctions (TJs) between blood-brain barrier (BBB) endothelial cells construct a robust physical barrier, whose damage underlies BBB dysfunctions related to several neurodegenerative diseases.
Esther Sasson, Shira Anzi, Batia Bell, Oren Yakovian, Meshi Zorsky, Urban Deutsch, Britta Engelhardt, Eilon Sherman, Gad Vatine, Ron Dzikowski, Ayal Ben-Zvi   +10 more
doaj   +1 more source

Impact of low birth weight and cardiovascular risk factors on endothelial function in early adult life

, 2001
Background: Low birth weight is related to increased risk of coronary heart disease in adults and recently has been associated with vascular endothelial dysfunction in children.
Leeson, Christopher, Kattenhorn, M, Morley, R., Deanfield, J.E., Leeson, CP, Deanfield, JE, Leeson, C.P.M., Kattenhorn, M., Morley, R, Lucas, A., Lucas, A   +10 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source