Results 41 to 50 of about 342,502 (309)

3-MA Inhibits Autophagy and Favors Long-Term Integration of Grafted Gad67–GFP GABAergic Precursors in the Developing Neocortex by Preventing Apoptosis

open access: yesCell Transplantation, 2014
In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature
Christian Roux   +8 more
doaj   +1 more source

Endothelium-independent effect of CNP on vascular reactivity.

open access: yes, 2016
Endothelium-independent effect of CNP on vascular reactivity.
Carolina Caniffi (444744)   +5 more
core   +1 more source

Impact of low birth weight and cardiovascular risk factors on endothelial function in early adult life [PDF]

open access: yes, 2001
Background: Low birth weight is related to increased risk of coronary heart disease in adults and recently has been associated with vascular endothelial dysfunction in children.
Morley, R.   +4 more
core   +1 more source

Endothelium-dependent and -independent aortic vascular relaxation in SED and EX mice.

open access: yes, 2019
A. Phenylephrine (PE)-mediated vascular contraction in aortic rings from SED and EX mice was expressed as a percentage maximum response to KPSS (n = 8 per group). B.
Peter F. Bodary (4173751)   +3 more
core   +1 more source

Endothelium-dependent vasorelaxation and morphology change of thoracic aorta.

open access: yes, 2016
Both endothelium-dependent vasorelaxation and morphology of thoracic aorta were measured in hyperhomocysteinemia rats, and anti-peroxynitrite treatment significantly alleviated endothelial injury induced by hyperhomocysteinemia.
Jiahui Xu (3156327)   +8 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Biology of the Endothelium [PDF]

open access: yesClinical Cardiology, 1997
The endothelium releases factors that control vascular relaxation and contraction, thrombogenesis and fibrinolysis, and platelet activation and inhibition. Maintaining the functional integrity of the endothelium, therefore, is critical for the preservation of blood flow and the prevention of thrombosis.
T F, Lüscher, M, Barton
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy

open access: yesNature Communications
Cancer-associated fibroblasts (CAFs) play a key role in cancer progression and treatment outcome. This study dissects the intra-tumoral diversity of CAFs in basal cell carcinoma, squamous cell carcinoma, and melanoma using molecular and spatial single ...
Agnes Forsthuber   +25 more
doaj   +1 more source

Lipids and the endothelium [PDF]

open access: yesCardiovascular Research, 1999
The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.
A M, Dart, J P, Chin-Dusting
openaire   +2 more sources

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