Results 31 to 40 of about 261,152 (266)

The corneal endothelium [PDF]

Eye, 1990
The endothelium is a monolayer of cells on the posterior corneal surface that transports water from the stroma into the anterior chamber. This movement of water counters a natural tendency for the stroma to swell and is necessary to maintain a transparent cornea.
S J, Tuft, D J, Coster
openaire   +2 more sources

High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate

Neurobiology of Disease, 2013
Glutamate excitotoxicity is a consolidated hypothesis in neonatal brain injuries and tissue plasminogen activator (t-PA) participates in the processes through proteolytic and receptor mediated effects.
Vincent Jean Henry, Maryline Lecointre, Vincent Laudenbach, Carine Ali, Richard Macrez, Amandine Jullienne, Vincent Berezowski, Peter Carmeliet, Denis Vivien, Stéphane Marret, Bruno José Gonzalez, Philippe Leroux   +11 more
doaj   +1 more source

Endoglin: Beyond the Endothelium [PDF]

Biomolecules, 2020
Keywords: endoglin; CD105 TGF-β; BMP9; ALK-1; TRC105; tumor ...
Schoonderwoerd, M.J.A., Goumans, M.J.T.H., Hawinkels, L.J.A.C.   +2 more
openaire   +4 more sources

3-MA Inhibits Autophagy and Favors Long-Term Integration of Grafted Gad67–GFP GABAergic Precursors in the Developing Neocortex by Preventing Apoptosis

Cell Transplantation, 2014
In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature
Christian Roux, Céline Lesueur, Caroline Aligny, Carole Brasse-Lagnel, Damien Genty, Stéphane Marret, Annie Laquerrière, Soumeya Bekri, Bruno J. Gonzalez   +8 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Biology of the Endothelium [PDF]

Clinical Cardiology, 1997
The endothelium releases factors that control vascular relaxation and contraction, thrombogenesis and fibrinolysis, and platelet activation and inhibition. Maintaining the functional integrity of the endothelium, therefore, is critical for the preservation of blood flow and the prevention of thrombosis.
T F, Lüscher, M, Barton
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy

Nature Communications
Cancer-associated fibroblasts (CAFs) play a key role in cancer progression and treatment outcome. This study dissects the intra-tumoral diversity of CAFs in basal cell carcinoma, squamous cell carcinoma, and melanoma using molecular and spatial single ...
Agnes Forsthuber, Bertram Aschenbrenner, Ana Korosec, Tina Jacob, Karl Annusver, Natalia Krajic, Daria Kholodniuk, Sophie Frech, Shaohua Zhu, Kim Purkhauser, Katharina Lipp, Franziska Werner, Vy Nguyen, Johannes Griss, Wolfgang Bauer, Ana Soler Cardona, Benedikt Weber, Wolfgang Weninger, Bernhard Gesslbauer, Clement Staud, Jakob Nedomansky, Christine Radtke, Stephan N. Wagner, Peter Petzelbauer, Maria Kasper, Beate M. Lichtenberger   +25 more
doaj   +1 more source

Lipids and the endothelium [PDF]

Cardiovascular Research, 1999
The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.
A M, Dart, J P, Chin-Dusting
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source