Results 31 to 40 of about 335,896 (308)

High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate

Neurobiology of Disease, 2013
Glutamate excitotoxicity is a consolidated hypothesis in neonatal brain injuries and tissue plasminogen activator (t-PA) participates in the processes through proteolytic and receptor mediated effects.
Vincent Jean Henry, Maryline Lecointre, Vincent Laudenbach, Carine Ali, Richard Macrez, Amandine Jullienne, Vincent Berezowski, Peter Carmeliet, Denis Vivien, Stéphane Marret, Bruno José Gonzalez, Philippe Leroux   +11 more
doaj   +1 more source

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function [PDF]

, 2002
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular disease. We investigated whether carriage of the polymorphism was associated with functional changes in the endothelium, and how genotype ...
Jeerooburkhan, N., Muller, D.P.R., Mullen, M.J., Deanfield, J.E., Muller, DP, Deanfield, JE, Humphries, SE, Kattenhorn, M., Cole, T.J., Lucas, A, Humphries, S.E., Leeson, Christopher, Kattenhorn, M, Hingorani, AD, Jeerooburkhan, N, Hingorani, S.D., Leeson, CP, Mullen, MJ, Leeson, C.P.M., Cole, TJ, Lucas, A.   +20 more
core   +1 more source

Endothelium-dependent effect of CNP on vascular reactivity.

, 2016
Endothelium-dependent effect of CNP on vascular reactivity.
Carolina Caniffi (444744), María L. Sueiro (3391457), María A. Costa (3391460), Cristina Arranz (444749), Flavia M. Cerniello (3391451), María N. Gobetto (3391454)   +5 more
core   +1 more source

3-MA Inhibits Autophagy and Favors Long-Term Integration of Grafted Gad67–GFP GABAergic Precursors in the Developing Neocortex by Preventing Apoptosis

Cell Transplantation, 2014
In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature
Christian Roux, Céline Lesueur, Caroline Aligny, Carole Brasse-Lagnel, Damien Genty, Stéphane Marret, Annie Laquerrière, Soumeya Bekri, Bruno J. Gonzalez   +8 more
doaj   +1 more source

Endothelium-independent effect of CNP on vascular reactivity.

, 2016
Endothelium-independent effect of CNP on vascular reactivity.
Carolina Caniffi (444744), María L. Sueiro (3391457), María A. Costa (3391460), Cristina Arranz (444749), Flavia M. Cerniello (3391451), María N. Gobetto (3391454)   +5 more
core   +1 more source

Endothelium-dependent vasorelaxation and morphology change of thoracic aorta.

, 2016
Both endothelium-dependent vasorelaxation and morphology of thoracic aorta were measured in hyperhomocysteinemia rats, and anti-peroxynitrite treatment significantly alleviated endothelial injury induced by hyperhomocysteinemia.
Jiahui Xu (3156327), Qi Sun (127), Huanyuan Wang (3156324), Kun Jiao (3156330), Yu Dong (398252), Huirong Liu (107006), Wen Wang (6570), Teng Liu (232251), Xin Liu (43569)   +8 more
core   +1 more source

Endothelium-dependent and -independent aortic vascular relaxation in SED and EX mice.

, 2019
A. Phenylephrine (PE)-mediated vascular contraction in aortic rings from SED and EX mice was expressed as a percentage maximum response to KPSS (n = 8 per group). B.
Peter F. Bodary (4173751), James A. Shayman (359510), Justin J. Kang (6730364), Taylour A. Treadwell (6730367)   +3 more
core   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang, Weber, Christian, Kim S. C. Weber, Weber, Kim S.C., Weber, Peter C., Wolfgang Erl, Peter C. Weber, Christian Weber   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Biology of the Endothelium [PDF]

Clinical Cardiology, 1997
The endothelium releases factors that control vascular relaxation and contraction, thrombogenesis and fibrinolysis, and platelet activation and inhibition. Maintaining the functional integrity of the endothelium, therefore, is critical for the preservation of blood flow and the prevention of thrombosis.
T F, Lüscher, M, Barton
openaire   +2 more sources