Clinical Characteristics and Outcomes of Non-Invasive Ventilation Following Unplanned Extubation in the Elderly ICU Patients: A Retrospective Cohort Study. [PDF]
Clin Interv AgingHsu YC, Chen HC, Li HH.
europepmc +1 more source
Changes in the Living Arrangements of Elderly People in Greece: 1974-1999 [PDF]
During the period 1974-1999 the percentage of elderly living with their children in Greece reduced from 55 per cent to about 32 per cent. In this paper we examine determinants of the decrease in intergenerational co-residence among Greek elderly people ...
Eleni Karagiannaki
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Digital Healthy Aging in China: Current Landscape and the Way Forward. [PDF]
Health Care SciQiu Y, Yao H, Ren P, Tian X, Gu X.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A preliminary analysis of prevalence and associated factors of dysphagia in hospitalized elderly patients with fractures. [PDF]
Front NeurolXie Y +6 more
europepmc +1 more source
Factors Influencing Productive Activities of the Korean Rural Elderly [PDF]
The purpose of this study was to identify the factors influencing productive activities of the Korean rural elderly. Utilizing data from the 2004 survey "Living Profile and Welfare Service Needs of Older Persons in Korea," this study predicted the ...
Ma, Sang-Jin
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies. [PDF]
Clin Transl MedZhang J +8 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source