Results 181 to 190 of about 3,263,574 (391)

PEMBERDAYAAN LANSIA MELALUI PENINGKATAN AKTIVITAS PRODUKTIF DI DESA JANGGAN KECAMATAN PONCOL KABUPATEN MAGETAN [PDF]

open access: yes
The aim of this research is to see how the Elderly Empowerment program is through Increasing Productive Activities in Janggan Village, Poncol District, Magetan Regency. In life, growing old is a certain thing.
Rivaldan, Muh. Januar Galang
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Quantitative assessment of baseline imbalances in evolocumab and alirocumab trials: a meta-epidemiological study

open access: yesBMC Medical Research Methodology
Background Baseline imbalances have been identified in randomized trials of evolocumab and alirocumab. Our aim was to quantitatively assess (1) the presence of systematic baseline differences, and (2) the relationship of baseline differences with effects
F. H. van Bruggen   +2 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Effects of activities participation on frailty of older adults in China

open access: yesFrontiers in Public Health
ObjectiveFrailty represents a significant health challenge among older adults, necessitating effective interventions to enhance their overall wellbeing.
Zihan Ni   +6 more
doaj   +1 more source

A study to ascertain the patients' satisfaction of the quality of hospital care in Greece compared with the patients' satisfaction in Poland [PDF]

open access: yes, 2007
PURPOSE: The aim of this study is to evaluate the satisfaction of elderly patients, of the hospital care's quality, based on the literature evidence on results of a qualitative research and on a previous developed conceptual frame.
Nikolaos, Triantafyliou   +2 more
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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