Results 191 to 200 of about 3,202,647 (392)

YTHDF2 mediates the protective effects of MG53 on myocardial infarction injury via recognizing the m6A modification of MG53

open access: yesJournal of Cardiothoracic Surgery
Introduction High levels of MG53 may attenuate the damage from myocardial infarction (MI). Furthermore, N6-methyl-adenosine (m6A) methylation is a mode of RNA modification that influences mRNA functions.
Zhaojie Li, Kai Li, Jianqiang Zhao
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Effects of Body Mass Index on Early Blood Pressure and Cardiac Structure and Function in the Elderly

open access: yesGuoji laonian yixue zazhi
Objective To investigate and analyze the effect of body mass index (BMI) on early changes of blood pressure and cardiac structure and function in the elderly.
Wenjing Wei, Xianglan Sun
doaj   +1 more source

Income mobility and deprivation dynamics among the elderly in Belgium and the Netherlands [PDF]

open access: yes
This paper analyzes the dynamics of income and deprivation among the elderly in Belgium and the Netherlands between 1985 and 1988. It appears that, in 1985, the average level of deprivation in Belgium and the Netherlands was about the same.
Dirven, H.J., Fouarge, D.
core   +1 more source

PENGARUH PEMBERIAN SUPLEMENTASI SUPEROXIDE DISMUTASE (SOD) TERHADAP KADAR ALBUMIN SERUM PADA LANSIA [PDF]

open access: yes, 2015
Background: Levels of serum albumin can be used as a predictor of morbidity and mortality in the elderly. Reduced serum albumin concentration can be caused by oxidative modification due to aging or insufficient protein intake.
Nalaresi, Andyta   +2 more
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

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