Results 221 to 230 of about 3,202,647 (392)
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
GERIATRICS IN OTOLARYNGOLOGY STATISTIC SUDIES ON 376 JAPANESE ELDERLY INDIVIDUALS
S Sawaki+3 more
openalex +2 more sources
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Effect of cyclandelate on mental function and cerebral blood flow in elderly patients. [PDF]
Jonathan Ball, Alex R. Taylor
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Incomes and inequality in the long run: the case of German elderly [PDF]
We employ German Sample Survey Income data to examine income inequality and the financial situation of elderly citizens for the period from 1978 to 2003, focussing on differences between retired and non-retired elderly and between elderly with residence ...
Bönke, Timm+2 more
core
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Association between urinary tract infections and anemia among the elderly in India: Insights from the longitudinal aging study. [PDF]
Hussain D, Barnwal J.
europepmc +1 more source
Comparison of mortality rates in elderly hypertensive and normotensive hemiplegic patients. [PDF]
J. D. Merrett, Gerry Adams
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source