Results 231 to 240 of about 3,202,647 (392)

Factors Contributing to the Diabetes Burden in the Elderly: A Clinical Perspective. [PDF]

Scand J Caring Sci
Çınar D, Düzgün G, Türeyen A, Akyol A.   +3 more
europepmc   +1 more source

Open-Heart Surgery on the Elderly [PDF]

, 1966
L. Thompson Bowles, Grady L. Hallman, Denton A. Cooley   +2 more
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Artificial Intelligence in Chronic Disease Management for Aging Populations: A Systematic Review of Machine Learning and NLP Applications. [PDF]

Int J Gen Med
Feng G, Weng F, Lu W, Xu L, Zhu W, Tan M, Weng P.   +6 more
europepmc   +1 more source

Income Transfers to the Elderly in East Asia: Testing Asian Values [PDF]

This article examines the role of family and the state in relation to the living standards of the elderly in East Asia. It tries to test whether familial arrangement according to Confucian ethics, which are still taken seriously in East Asia, secures the
Huck-ju Kwon
core  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Young and Old Competing for Public Welfare Services [PDF]

Generational conflict affects the supply of public welfare services, and the rising share of elderly is seen as a threat to educational spending. We offer an analysis of spending in child care, primary and lower secondary education, and care for the ...
Jørn Rattsø, Lars-Erik Borge
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Effective Dosage of Ciprofol for the Induction of General Anesthesia Across Diverse Age Groups in Adults: A Single-Center, Prospective, Non-Randomized Sequential Trial. [PDF]

J Pain Res
Deng L, Zhang C, Tan M, Zeng W, Luo G, Li P.   +5 more
europepmc   +1 more source

Short‐Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

New England Journal of Medicine, 2017
J. Perry, N. Laperriere, C. O'Callaghan, A. Brandes, J. Menten, C. Phillips, M. Fay, R. Nishikawa, G. Cairncross, W. Roa, D. Osoba, J. Rossiter, A. Sahgal, H. Hirte, F. Laigle-Donadey, E. Franceschi, O. Chinot, V. Golfinopoulos, L. Fariselli, A. Wick, L. Feuvret, M. Back, M. Tills, C. Winch, B. Baumert, W. Wick, K. Ding, W. Mason   +27 more
semanticscholar   +1 more source