Results 241 to 250 of about 3,202,647 (392)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Blood pressure control in Türkiye: A primary healthcare pilot study

Preventive Medicine Reports
Hypertension is present in almost a third of Türkiye’s adult population. The Ministry of Health of the Republic of Türkiye in conjunction with the World Health Organization, rolled out a pilot primary health care model from February 2019 to 2020 to ...
Banu Ekinci, Saion Chatterjee, Ilayda Ucuncu, Zubeyde Ozkan Altunay, Tufan Nayir, Secil Sis, Esin Yilmaz Aslan, Nevin Cobanoglu, Gulay Sarıoglu, Fatma Tamkoc Gurbuzturk, Sila Toker, Secil Ozkan, Toker Erguder   +12 more
doaj  

Relating Health and Social Contacts to the Morale of Elderly Persons [PDF]

, 1969
Ilse J. Volinn, Jess B. Spielholz
openalex   +1 more source

Labour Migration and Time Use Patterns of the Left-Behind Children and Elderly in Rural China [PDF]

Rural-urban migration has become a major feature of the Chinese economy since the mid-1990s. Due to institutional arrangements and economic and cultural factors, massive labor migration has resulted in a large left-behind population consisting of ...
Fiona MacPhail, Hongqin Chang, Xiao-yuan Dong   +2 more
core  

Nitrazepam and the elderly. [PDF]

BMJ, 1972
E H Jarvis, J G Evans
openaire   +5 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Ten-Year Trends in Pelvic Fractures Among China's Aging Population: A Retrospective Single-Center Study. [PDF]

Med Sci Monit
Xiao H, Gao F, Chen Y, Peng W, Liu G, Cui T, Zhang J, Yang M, Wu X.   +8 more
europepmc   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Construction and Validation of Risk Scoring Model for Inadequate Bowel Preparation in Elderly Patients Undergoing Colonoscopy. [PDF]

Ther Clin Risk Manag
Xu Y, Ou S, Yuan X, Yao J, Yang T.
europepmc   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source