Results 21 to 30 of about 786,116 (247)

What is important to the GP in recognizing acute appendicitis in children: a delphi study

BMC Primary Care, 2023
Background For diagnostic research on appendicitis in registration data, insight is needed in the way GPs generate medical records. We aimed to reach a consensus on the features that GPs consider important in the consultation and medical records when ...
Guus C.G.H. Blok, Marjolein Y. Berger, Arjan B. Ahmeti, Gea A. Holtman   +3 more
doaj   +1 more source

Effect of faecal calprotectin testing on referrals for children with chronic gastrointestinal symptoms in primary care: study protocol for a cluster randomised controlled trial

BMJ Open, 2021
Introduction Children with chronic gastrointestinal symptoms are frequently seen in primary care, yet general practitioners (GPs) often experience challenges distinguishing functional gastrointestinal disorders (FGID) from organic disorders.
Patrick Ferry van Rheenen, Sophie Ansems, Marjolein Berger, Karin Vermeulen, Gina Beugel, Maria Couwenberg, Gea Holtman   +6 more
doaj   +1 more source

Supporting carers of stroke survivors to reduce carer burden: development of the Preparing is Caring intervention using Intervention Mapping

BMC Public Health, 2019
Background Burden is well documented among carers of stroke survivors, yet current evidence is insufficient to determine if any strategies reduce this negative outcome.
Jessica F. Hall, Thomas F. Crocker, David J. Clarke, Anne Forster   +3 more
doaj   +1 more source

Lactoferrin-Loaded PEG/PLA Block Copolymer Targeted With Anti-Transferrin Receptor Antibodies for Alzheimer Disease

Dose-Response, 2020
Last few years, struggles have been reported to develop the nanovesicles for drug delivery via the brain–blood barrier (BBB). Novel drugs, for instance, iAβ 5 , are efficient to inhibit the aggregates connected to the treatment of Alzheimer disease and ...
Guichen Li, Xianghong Sun, Xiaona Wan, Dongming Wang   +3 more
doaj   +1 more source

Anaemia and associated factors among older adults in an urban district in China: a large-scale cross-sectional study

BMJ Open, 2022
Objective Anaemia leads to poor health outcomes in older adults; however, most current research in China has focused on younger adults. This study aimed to investigate the prevalence of anaemia and its associated factors in older adults in an urban ...
Wenqing Ni, Xueli Yuan, Jian Xu, Hongmin Zhang, Yuanying Sun   +4 more
doaj   +1 more source

Progress of Acetyltransferase Gene Naa10 in Cancer

Zhongliu Fangzhi Yanjiu, 2019
N-α-terminal acetyltransferase gene 10 (Naa10) is extensively expressed in eukaryotic cells, and its encoded Naa10p is the catalytic subunit of the NatA complex.
HE Zukun, QIU Youyu, BAI Song, YANG Hongju   +3 more
doaj   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Algorithm-associated digital addiction among older adults: mechanisms and public health implications for healthy aging

Frontiers in Public Health
ObjectiveTo examine how algorithmic inducement mechanisms are associated with digital addiction among Chinese adults aged 60 and above.MethodsA cross-sectional survey was conducted among older users of major Chinese digital platforms.
Zhaoxue Li, Xiaoyong Yu, Xiaoyong Yu, Xiaoyong Yu, Kan Tian, Kan Tian, Kan Tian   +6 more
doaj   +1 more source

Physiotherapy plus conventional treatment versus conventional treatment only in the treatment of functional constipation in children: design of a randomized controlled trial and cost-effectiveness study in primary care

BMC Pediatrics, 2018
Background Our aim was to design a study to evaluate the effectiveness and cost-effectiveness of adding physiotherapy to conventional treatment for children with functional constipation in primary care.
Jojanneke J. G. T. van Summeren, Gea A. Holtman, Yvonne Lisman- van Leeuwen, Lisa E. A. M. Louer, Alice H. C. van Ulsen-Rust, Karin M. Vermeulen, Boudewijn J. Kollen, Janny H. Dekker, Marjolein Y. Berger   +8 more
doaj   +1 more source