Results 11 to 20 of about 508,146 (267)

A Case of Multiple Liver Metastases after Surgery in Elderly HER2-Positive Breast Cancer in Which Anastrozole + Trastuzumab Was Ineffective but T-DM1 Was Effective

Case Reports in Oncology, 2021
Chemotherapy is often difficult to treat human epidermal growth factor receptor 2 (HER2)-positive metastatic recurrent breast cancer in the elderly, and no standard treatment has been established at this point. We experienced a case in which trastuzumab (
Tomohiro Shidahara, Shozo Ohsumi, Yuichiro Miyoshi, Mina Takahashi, Seiki Takashima, Kenjiro Aogi, Norihiro Teramoto   +6 more
doaj   +1 more source

The long‐term survival of esophageal cancer in elderly patients: A multi‐center, retrospective study from China

Cancer Medicine, 2023
Background Esophageal cancer (EC) often occurs in the elderly, and approximately 40% of patients are 70 years or older. To investigate the long‐term survival of EC in elderly patients, to provide a theoretical direction for better management and ...
Runhua Li, Yutong He, Xibin Sun, Ning Wang, Min Zhang, Kuangrong Wei, Huizhang Li, Peng Dong, Lingbin Du, Wanqing Chen   +9 more
doaj   +1 more source

A relevance of a differentiated approach to glycemic goals achievement in old patients with type 2 diabetes mellitus and cardiovascular diseases [PDF]

КардиоСоматика, 2018
Today patient’ self-monitoring of blood glucose is considered one of the main components in the management of diabetes mellitus. The article deals with possibilities of modern means for glycemia self-monitoring.
T. I Safronova
doaj   +1 more source

The clinical outcomes of elderly acute leukemia patients receiving allogenic hematopoietic stem cell transplantation and application of comprehensive nursing care

Zhongguo shuxue zazhi, 2022
Objective To investigate the clinical outcomes of allogeneic hematopoietic stem cell transplantation in elderly patients with acute leukemia and the role of comprehensive nursing.
Yanting GU, Feng WEI, Chao MA, Xiaming ZHU, Ting XU   +4 more
doaj   +1 more source

Defective Granuloma Formation in Elderly Infected Patients

Frontiers in Cellular and Infection Microbiology, 2020
Granulomas are compact structures formed in tissues by the immune system in response to aggressions. The in vitro formation of granulomas using circulating mononuclear cells is an innovative method to easily assess the immune response of patients ...
Aurélie Daumas, Aurélie Daumas, Benjamin Coiffard, Céline Chartier, Amira Ben amara, Julie Alingrin, Patrick Villani, Jean-Louis Mege   +7 more
doaj   +1 more source

Factors determining the clinical significance of dipeptidyl peptidase-4 inhibitors in the treatment of elderly patients with type 2 diabetes mellitus

Медицинский совет, 2021
Elderly patients with diabetes type 2 represent complex and heterogeneous group with different diabetes complications and comorbidity, polypharmacy, functional and cognitive state.
I. V. Glinkina, A. V. Balashova, A. S. Shyman, A. V. Oderij, S. A. Khan, G. E. Runova, T. B. Morgunova, V. V. Fadeev   +7 more
doaj   +1 more source

Real‐world data on the efficacy and safety of immune‐checkpoint inhibitors in elderly patients with non‐small cell lung cancer

Cancer Medicine, 2023
Purpose Immune‐checkpoint inhibitors (ICIs) are effective against advanced non‐small cell lung cancer (NSCLC). However, whether the efficacy and safety of ICI treatment in elderly patients are similar to those in younger patients is unclear.
Daisuke Morinaga, Hajime Asahina, Shotaro Ito, Osamu Honjo, Hisashi Tanaka, Ryoichi Honda, Hiroshi Yokouchi, Keiichi Nakamura, Kei Takamura, Fumihiro Hommura, Yasutaka Kawai, Kenichiro Ito, Noriaki Sukoh, Keiki Yokoo, Ryo Morita, Toshiyuki Harada, Taichi Takashina, Tomohiro Goda, Hirotoshi Dosaka‐Akita, Hiroshi Isobe, the Hokkaido Lung Cancer Clinical Study Group Trial   +20 more
doaj   +1 more source

Acute atrial fibrillation in emergency surgery:Is it rare?

Indian Journal of Anaesthesia, 2011
Atrial fibrillation (AF) is a common arrhythmia with an estimated clinical prevalence of approximately 1% in the general population and as high as 9% in individuals by the age of 80 years. The aetiology is multifactorial.
Saravanan Ankichetty, Amar Nandhakumar, Rajeev Subramanyam, Lashmi Venkatraghavan   +3 more
doaj   +1 more source

Creatinine-normalized urinary lipocalin-2 in children with obesity: association with insulin resistance in a cross-sectional study

Scientific Reports
Childhood obesity is associated with insulin resistance and early cardiometabolic risk. Lipocalin-2 (LCN2), a biomarker linked to inflammation, metabolic regulation, and renal tubular stress, has been proposed as a potential indicator of obesity-related ...
Aydin Celik, Busra Karadag Celik
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source