Results 131 to 140 of about 7,855,345 (303)
We are approaching a period when the numbers of old people in Ireland are expected to increase significantly and the numbers of the very old will grow quite dramatically.
Hughes, Jenny +1 more
core
Aim. To study the effects of skeletal electromyostimulation (SEMS) on intracardiac hemodynamics and arrhythmia risk in elderly patients with myocardial infarction (MI). Material and methods.
A. N. Sumin +4 more
doaj
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Mental disorders in older Irish people: incidence, prevalence and treatment.
This study on mental disorders in older Irish people is a further contribution to work by the National Council for the Elderly on the health and well-being of older people.
National Council for the Elderly +2 more
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Voluntary-statutory partnership in community care of the elderly
The National Council for the Elderly was established in January 1990 in succession to the National Council for the Aged which began in June ...
Mulvihill, Ray
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
In recent years dementia has beconie more common as increasing numbers of people are reaching advanced old age. The relative absence of services specifically designed to cope with the condition poses problems for sufferers, carers and service ...
National Council for the Elderly
core
Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]
Song S, Du H, Lu X, Luo B, Li Z.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

