Results 181 to 190 of about 1,481,214 (358)

Impact of loneliness on mental and clinical status in elderly patients with cardiovascular disease

N. I. Zhernakova, D. T. Lebedev, T. Yu. Lebedev, M. A. Kosov   +3 more
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dupilumab in Elderly Patients with Atopic Dermatitis-A Systematic Review and Meta-Analysis. [PDF]

Biomedicines
Hałubiec P, Gołąbek N, Wojas-Pelc A, Szepietowski JC, Jaworek AK.   +4 more
europepmc   +1 more source

Three-year Outcomes of Endothelial Keratoplasty in Late-Stage Elderly Versus Younger Patients

Masatoshi Hirayama, Risa Yamazaki-Hokama, Takanori Suzuki, Kazuno Negishi   +3 more
openalex   +1 more source

Efficacy and safety of low-dose imatinib in an elderly patient with mixed phenotype acute leukemia with t(9;22)(q34;q11.2);BCR-ABL1 [PDF]

, 2020
Yusuke Okayama, Teruhito Takakuwa, Ippei Otomaru, Mirei Horiuchi, Akiko Miura, Taku Araki, Yotaro Fujitani, Ryosuke Yamamura   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Gender differences in management of myocardial infarction in elderly patients [PDF]

Gonçalo Cordeiro Ferreira, J G Fiuza, M Almeida, Fernando Pimentel‐Santos, O Kungel, J G Pereira, Lucas Cândido Gonçalves, Bruno Marmelo, Antônio de Lisboa Lopes Costa   +8 more
openalex   +1 more source

P626 Higher discontinuation rates of anti-TNF therapy in elderly IBD patients compared with a younger age group: results from a prospective registry [PDF]

, 2019
Lisa Smits, Maarten F. de Jong, Nathan den Broeder, M. Russel, Tessa E H Römkens, Robert West, Jeroen M. Jansen, Frank Hoentjen   +7 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source