Results 41 to 50 of about 492,775 (312)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nursing care related to fall prevention among hospitalized elderly people: an integrative review
Revista Brasileira de Enfermagem, 2021 Objective: to identify scientific productions on nursing care related to fall risk prevention among hospitalized elderly people. Methods: an integrative literature review from 2015 to 2019 in the PubMed/MEDLINE, Scopus, Web of Science, LILACS, BDENF ...
Adnairdes Cabral de Sena +3 more
doaj +2 more sources
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Europe's Journal of Psychology, 2017 Sentimentality and nostalgia are two similar psychological constructs, which play an important role in the emotional lives of elderly people who are usually focused on the past. There are two objectives of this study - making cross-cultural comparison of
Stanislava Yordanova Stoyanova +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of public transport in addressing sustainable mobility for the elderly population in Malta [PDF]
, 2013 Over the past few years, several countries have continued experiencing a growth in their elderly population. Similarly, a number of towns and villages in Malta registered a high elderly population in the last census (NSO, 2012).
Mifsud, Deborah, Attard, Maria
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A public health approach to social isolation in the elderly [PDF]
, 2020 The recent pandemic has highlighted the impact of social isolation on health. District and community nurses are in daily contact with vulnerable, elderly clients for whom the norm is a world with little social contact.
Gould, J.
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Rural and Remote Health, 2021 Introduction: There is a high prevalence of elderly people aged 65 years and older with disabilities in low- and middle-income countries, including Indonesia. This study examined urban-rural disparities in disabilities among elderly Indonesian people by
Mardiana Puspitasari +3 more
doaj +1 more source