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Creating Global Citizens through Encounters with Asia—The Making of the Modern World Program at Eleanor Roosevelt College, UCSD

The ASIANetwork Exchange: A Journal for Asian Studies in the Liberal Arts, 2020
This article describes the “Making of the Modern World” program, a liberal arts curriculum in a public university. Thirty years ago Eleanor Roosevelt College at the University of California, San Diego, developed a multi-disciplinary liberal arts core ...
Richard Madsen
doaj +2 more sources

State Capture through Corruption: Can Human Rights Help?

AJIL Unbound, 2019
Until recently, the United Nations and regional systems of human rights protection had shown considerable reluctance to address human rights violations resulting from corruption. Instead, these actors would underline the negative impacts of corruption on
Jimena Reyes
doaj +1 more source

Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer

Cells, 2022
Head and neck squamous cell carcinoma (HNSCC) represents a highly prevalent and deadly malignancy worldwide. The prognosis for locoregionally advanced HNSCC has not appreciably improved over the past 30 years despite advances in surgical, radiation, and ...
Farhoud Faraji +4 more
doaj +1 more source

On the Status of Rights

Voices in Bioethics, 2021
Photo by Patrick Tomasso on Unsplash ABSTRACT In cases where the law conflicts with bioethics, the status of rights must be determined to resolve some of the tensions.
Liam Butchart
doaj +1 more source

Eleanor Roosevelt’s Peculiar Pacifism: Activism, Pragmatism, and Political Efficacy in Interwar America

European Journal of American Studies, 2017
In the interwar years, American women have played a major role in shaping both the domestic and the international debate on peace, by spreading pacifist tenets and merging them with the promotion of social justice and human rights. Leading figures of the
Dario Fazzi
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Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +295 more
wiley +1 more source

C-terminal binding proteins: central players in development and disease

Biomolecular Concepts, 2014
C-terminal binding proteins (CtBPs) were initially identified as binding partners for the E1A-transforming proteins. Although the invertebrate genome encodes one CtBP protein, two CtBPs (CtBP1 and CtBP2) are encoded by the vertebrate genome and perform ...
Stankiewicz Trisha R. +3 more
doaj +1 more source

Complement Activation Linked to Type II Interferon Signaling in Still Disease

Arthritis &Rheumatology, EarlyView.
Objective Still disease (SD) is an autoinflammatory syndrome characterized by innate immune dysregulation. Although complement can drive inflammation, its involvement in SD remains to be defined. Thus, we aimed to assess complement activation in SD. Methods Complement was assessed using transcriptomic, proteomic, and in vitro approaches. RNA sequencing
Freya M. C. H. Huijsmans +115 more
wiley +1 more source

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune‐mediated inflammatory arthritis and ageing

Arthritis &Rheumatology, Accepted Article.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/Endosialin is expressed by fibroblasts in the synovium, is highly upregulated during inflammation and has been proposed as a potential therapeutic target.
Samuel Kemble +12 more
wiley +1 more source

Electroconvulsive Therapy for Catatonia in Autistic and Non‐Autistic Patients: An Observational Study on Course, Efficacy, Aggression, and Self‐Injury Outcomes

Autism Research, EarlyView.
ABSTRACT Catatonia occurs disproportionately in autistic individuals and may respond to electroconvulsive therapy (ECT), yet prior reports suggest greater treatment burden in this population. We compared longitudinal ECT utilization, safety, and clinical outcomes between autistic and non‐autistic patients with catatonia.
Joshua Ryan Smith +15 more
wiley +1 more source

16. peace & justice
5. gender equality
history america

cold war
united nations