Results 81 to 90 of about 165,009 (328)

Clinicopathological determinants of an elevated systemic inflammatory response following elective potentially curative resection for colorectal cancer [PDF]

, 2017
Introduction: The postoperative systemic inflammatory response (SIR) is related to both long- and short-term outcomes following surgery for colorectal cancer.
Horgan, Paul G., McMillan, Donald C., McSorley, Stephen T., Park, James H., Ramanathan, Michelle L., Walley, Killian, Watt, David G.   +6 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Balancing revenue generation with capacity generation: case distribution, financial impact and hospital capacity changes from cancelling or resuming elective surgeries in the US during COVID-19

BMC Health Services Research, 2020
Background To increase bed capacity and resources, hospitals have postponed elective surgeries, although the financial impact of this decision is unknown.
Joseph E. Tonna, Heidi A. Hanson, Jessica N. Cohan, Marta L. McCrum, Joshua J. Horns, Benjamin S. Brooke, Rupam Das, Brenna C. Kelly, Alexander John Campbell, James Hotaling   +9 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Challenges and Solutions during the COVID-19 Pandemic: Hospitalization and Performance in Elective Pediatric Surgeries

Medicina
Background and Objectives: This retrospective study aimed to investigate the impact of the COVID-19 pandemic on the most frequently performed elective pediatric surgical procedures and the number of hospitalizations and compare it to the pre-pandemic and
Miro Jukić, Petra Tokić, Sara Elezović Baloević, Zenon Pogorelić   +3 more
doaj   +1 more source

QUEUE PROFILE FOR PEDIATRIC SCOLIOSIS SURGERY IN A REFERENCE HOSPITAL IN THE BRAZIL’S MIDWEST

Coluna/Columna, 2023
Objective: To describe the epidemiological profile of the list of patients with pediatric scoliosis (0 to 18 years old) treated at a tertiary public hospital in the Midwest Region.
SINVAL DORNELES FILHO, MURILO TAVARES DAHER, MATEUS BERGAMO LOMAZ, LUCAS LODOMIRO MELO, JULIANE LEITE ORCINO, NATHALIA AIDAR BITTAR, GABRIEL JOãO FRANCISCO DE SOUZA, THIAGO VINíCIUS DE ASSIS MORAES, PEDRO FELISBINO JúNIOR, PAULO HENRIQUE MARTINS SILVA   +9 more
doaj   +1 more source

Resuming Elective Paediatric Surgical Procedures in the Era of COVID-19

African Journal of Paediatric Surgery, 2021
Background: The novel coronavirus and the disease it causes COVID-19, like other viral outbreaks, have an unpredictable timeline. Therefore, a triumph in the battle against COVID-19 could only be achieved if a health care system's capacity to support a potentially overwhelming increase in critical patient care needs is ...
Al-Omar, Khaled, Bakkar, Sohail
openaire   +2 more sources

Enhanced recovery after surgery [PDF]

, 2015
Enhanced Recovery or Fast Track Recovery after Surgery protocols (ERAS) have significantly changed perioperative care following colorectal surgery and are promoted as reducing the stress response to surgery.
Horgan, Paul G., McMillan, Donald C., McSorley, Stephen T., Watt, David G.   +3 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source