Results 31 to 40 of about 182,322 (263)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Electric field distribution of optimized composite insulator profiles under different pollution conditions

Ain Shams Engineering Journal, 2018
This paper presents the simulation results of electric field distribution for optimally designed medium voltage composite insulators under polluted conditions with and without water droplets.
El-Sayed M. El-Refaie, M.K. Abd Elrahman, M. Kh. Mohamed   +2 more
doaj   +1 more source

Differences between triggered lightning striking to ground and distribution line inferred from measured currents and electromagnetic fields

High Voltage, 2022
In 2018–2019, two types of rocket‐triggered lightning tests, that is, striking to ground and distribution line, were conducted in Guangdong, China. The main focus of this paper is to compare the waveform parameters of the return strokes (RS) from the two
Li Cai, Qiang Hu, Jianguo Wang, Mi Zhou, Quanxin Li, Rui Su, Yijun Huang   +6 more
doaj   +1 more source

The Distribution of Electrons in a Uniform Electric Field [PDF]

Australian Journal of Physics, 1995
Experiments are under way at the University of New England to measure the optical absorption of excited gas particles in a pre-breakdown discharge. Such measurements can be used to deduce the number density of electrons in the discharge. By comparing this experimental density map with the predictions of theory, electron transport parameters may be ...
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysis of the influence of configuration parameters on the electric field distribution of the main insulation structure of valve‐side winding of converter transformer considering electro‐thermal coupling

IET Electric Power Applications
The variation of configuration parameters in the insulation structure of transformers significantly impacts the distribution of electric fields. Current research on electric field distribution calculations often overlooks the influence of electric field ...
Lijun Yang, Zhidong Cheng, Li Cheng, Ruijin Liao   +3 more
doaj   +1 more source

Study on electric field distribution characteristics of the maintenance area when UHV AC transmission line crossing 220 kV tower

The Journal of Engineering, 2019
With the rapid development of China's power grid, it is becoming increasingly common that the multi-circuit overhead transmission lines cross over each other.
Feng Huo, Wei Lu, Zhibin Qiu, Daochun Huang, Congpeng Huang   +4 more
doaj   +1 more source

Grading ring parameters optimization for 220 kV metal‐oxide arrester using 3D‐FEM method and bat algorithm

IET Science, Measurement & Technology, 2021
Aging of metal oxide surge arresters is mainly affected by the high electric stress near the high voltage electrode. It has been observed that the distribution of voltage and electric field along an arrester is non‐uniform.
Nadjim Alti, Abdelhafid Bayadi, Khaled Belhouchet   +2 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source