Results 31 to 40 of about 193,944 (306)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A method for measuring surface electric field intensity of insulators based on electroluminescent effect

Energy Reports, 2020
The measurement for the surface electric field intensity of insulators based on electroluminescent effect is a non-contact measurement. By spraying a coating of epoxy paint mixed with ZnS:Cu electroluminescence powder on the surface of insulators, the ...
Xinyi Yang, Yunfei Jia, Lu Gao, Shengchang Ji, Zhibing Li   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Electric field control in DC cable test termination by nano silicone rubber composite

AIP Advances, 2017
The electric field distributions in high voltage direct current cable termination are investigated with silicone rubber nanocomposite being the electric stress control insulator.
Shu-Wei Song, Zhongyuan Li, Hong Zhao, Peihong Zhang, Baozhong Han, Mingli Fu, Shuai Hou   +6 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Electric field distribution of optimized composite insulator profiles under different pollution conditions

Ain Shams Engineering Journal, 2018
This paper presents the simulation results of electric field distribution for optimally designed medium voltage composite insulators under polluted conditions with and without water droplets.
El-Sayed M. El-Refaie, M.K. Abd Elrahman, M. Kh. Mohamed   +2 more
doaj   +1 more source

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

International Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir, Sarah Mechhoud, Taous‐Meriem Laleg‐Kirati   +2 more
wiley   +1 more source

Analysis of the influence of configuration parameters on the electric field distribution of the main insulation structure of valve‐side winding of converter transformer considering electro‐thermal coupling

IET Electric Power Applications
The variation of configuration parameters in the insulation structure of transformers significantly impacts the distribution of electric fields. Current research on electric field distribution calculations often overlooks the influence of electric field ...
Lijun Yang, Zhidong Cheng, Li Cheng, Ruijin Liao   +3 more
doaj   +1 more source

Study on electric field distribution characteristics of the maintenance area when UHV AC transmission line crossing 220 kV tower

The Journal of Engineering, 2019
With the rapid development of China's power grid, it is becoming increasingly common that the multi-circuit overhead transmission lines cross over each other.
Feng Huo, Wei Lu, Zhibin Qiu, Daochun Huang, Congpeng Huang   +4 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source