Results 31 to 40 of about 9,947,342 (284)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Analysis of the influence of the grounding method on the measurement of direct current total electric field on a civil housing platform

IET Generation, Transmission & Distribution, 2023
Buildings near direct current transmission lines are sensitive to the electromagnetic environment, and the measurement of the electric field above them is important in engineering design and environmental assessment in China.
Xu Jilai, Gao Keli, Wan Baoquan, Lu Yao, Zhang Liang   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Analysis of emission tests of electromagnetic disturbances in diesel-electric locomotives [PDF]

MATEC Web of Conferences, 2019
This paper discussed the measurement of radiated emissions of electromagnetic disturbances generated by diesel electric locomotive system. The measurement methodology, permissible values of a magnetic and electric field according to EN 50121-3-1 standard
Białoń Andrzej, Białek Kamil, Wetoszka Patryk   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Electric Field Measurements Made in Space

Geophysical Research Letters
Abstract The operating principles of a DC and low frequency electric field detector are developed, after which, examples of earlier important electric field measurements are presented, including, the first observation of parallel electric fields in the auroral acceleration region, the first observation of time domain structures in ...
F. S. Mozer, O. V. Agapitov
openaire   +2 more sources

Intrinsic, multiplexable sensors for electric field strength using structural slow light in phase-shifted fibre Bragg gratings [PDF]

, 2012
In this paper we demonstrate through simulation the potential for phase-shifted fibre Bragg gratings incorporating structural slow light to enable intrinsic reflection-mode point sensors for electric field or voltage.
Philip Orr, Niewczas, Pawel, Paweł Niewczas, Orr, Philip   +3 more
core   +4 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source