Results 41 to 50 of about 55,866 (265)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Body Composition of Medical Staff Working on Shift Duty and Day Duty: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The necessity for 24-hour patient care in the medical field often requires staff to work in shifts, disrupting their circadian rhythms controlled by the hypothalamus’s Suprachiasmatic Nuclei (SCN).
Avi Borkhatariya, Devendra Manohar Patil
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Modelling of high frequency bearing voltage for dual‐winding permanent magnet synchronous generators

IET Electric Power Applications
The modelling and analysis of high‐frequency bearing voltage are of great significance to the assessment and mitigation of the electrical erosion risk in wind power systems.
Zhihao Li, Ruifang Liu, Liangliang Zhang, Weili Li, Shulin Li, Xin Huang   +5 more
doaj   +1 more source

Global and Regional Ventilation during High Flow Nasal Cannula in Patients with Hypoxia [PDF]

Acute and Critical Care, 2018
Background High flow nasal cannula (HFNC) is known to increase global ventilation volume in healthy subjects. We sought to investigate the effect of HFNC on global and regional ventilation patterns in patients with hypoxia.
Dong Hyun Lee, Eun Young Kim, Ga Jin Seo, Hee Jung Suh, Jin Won Huh, Sang-Bum Hong, Younsuck Koh, Chae-Man Lim   +7 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

MODELO MATEMÁTICO DE IMPEDANCIA ELÉCTRICA DE UN YACIMIENTO DE CRUDO PESADO

Revista Fuentes El Reventón Energético, 2010
The main interest of this work consists on the formulation of a mathematical model of electric impedance for heavy oil reservoir, validated with the help of impedance measurements in rock-fluid plugs previously characterized with regard to its properties,
Diego Antonio Saray, Julio Cesar Perez, Manuel Cabarcas Simancas   +2 more
doaj  

Evaluación de la composición corporal de adultos sanos por antropometría e impedancia bioeléctrica

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La antropometría y el análisis de la impedancia bioeléctrica o bioimpedancia son métodos de campo ampliamente utilizados en nuestro medio para la evaluación de la composición corporal; a pesar de ello, se desconoce si generan resultados ...
Juan Carlos Aristizábal, María Teresa Restrepo, Alejandro Estrada   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source