Results 31 to 40 of about 21,780 (269)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Modern electric machines and drives for wind power generation: A review of opportunities and challenges

open access: yesIET Renewable Power Generation, 2021
With ever‐increasing concerns on energy crisis and environmental protection, there is a fast‐growing interest in wind power generation systems. As electric machines and drives are core components in wind turbines, it is a pressing need for researchers ...
Hao Chen   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Thermal models of electric machines with dynamic workloads

open access: yesLandtechnik, 2015
Electric powertrains are increasingly used in off-highway machines because of easy controllability and excellent overall efficiency. The main goals are increasing the energy efficiency of the machine and the optimization of the work process.
Christian Pohlandt, Marcus Geimer
doaj   +1 more source

Study on impact of gap difference on plasma distribution of direct current vacuum circuit breaker with double-break

open access: yesAIP Advances, 2023
During the fault current breaking process of a mechanical direct current vacuum circuit breaker (DC VCB) with double-break (DB), the mechanism’s dispersion can result in a gap difference between the two breaks. A DB DC VCB breaking experiment platform is
Chongyang Huang   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Advanced gate driving concepts and switching optimization for SiC semiconductors

open access: yesAutomatika
Silicon carbide (SiC) MOSFETS are increasingly favoured in power electronics for their improved properties compared to silicon-based counterparts, such as IGBTs.
Tomislav Ivaniš   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Optimal Compensation of Voltage Drop Across Long Power Cable in Motor Drive Systems: A Vector Controlled Approach

open access: yesIET Electric Power Applications
This paper proposes an optimal voltage compensation method for the drop across long power cable in a motor drive system. In the proposed method the drive is utilised to compensate the voltage drop and no additional voltage regulation device is required ...
Mesaad Albader   +2 more
doaj   +1 more source

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