Results 141 to 150 of about 99,375 (350)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Effect of Electroencephalograph Bionic Electrical Stimulation on Brainstem Auditory Evoked Potential and Somatosensory Evoked Potential in Persistent Vegetative State Patients

open access: yes康复学报, 2015
Objective:To study the effect of electroencephalograph bionic electric stimulating the points of Wangu(GB 12), Tianzhu(BL 10)and Neiguan(PC 6)on the auditory evoked potential(BAEP)and somatosensory evoked potential(SEP)in persistent vegetative state(PVS ...
Yingying NI   +10 more
doaj  

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

open access: yesAdvanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner   +12 more
wiley   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

open access: yesAdvanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint   +6 more
wiley   +1 more source

Progress on responsive neurostimulation in treatment of drug⁃resistant epilepsy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Epilepsy is a common chronic neurological disorder that severely impacts the quality of life and social functioning. Approximately 1/3 of patients are diagnosed with drug⁃resistant epilepsy (DRE), for which conventional antiepileptic seizure medicine ...
FAN Xiu⁃liang   +3 more
doaj   +1 more source

Low-level laser therapy and transcutaneous electric nerve stimulation in the management of temporomandibular disorders

open access: diamond, 2016
Karthikeya Patil   +4 more
openalex   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

open access: yesAdvanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo   +4 more
wiley   +1 more source

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