Results 141 to 150 of about 290,855 (374)

Modelling the positioning of single needle electrodes for the treatment of breast cancer in a clinical case [PDF]

open access: yes, 2015
Background: Breast cancer is the most common cancer in women worldwide and is the second most common cause of cancer death in women. Electrochemotherapy (ECT) used in early-phase clinical trials for the treatment of primary breast cancer resulted in a ...
Claudio, Botti   +8 more
core  

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput   +5 more
wiley   +1 more source

Laser‐Induced Graphene‐Assisted Patterning and Transfer of Silver Nanowires for Ultra‐Conformal Breathable Epidermal Electrodes in Long‐Term Electrophysiological Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a novel method using laser‐induced graphene (LIG) to enable high‐yield transfer of silver nanowire (AgNW) networks onto ultra‐low modulus, breathable silicone substrates. This approach creates ultra‐conformal epidermal electrodes (≈50 µm) for long‐term, high‐fidelity electrophysiological monitoring, even in challenging conditions ...
Jiuqiang Li   +10 more
wiley   +1 more source

Observation on Therapeutic Effect of Scalp Acupuncture Combined with Transcutaneous Electric Nerve Stimulation on Thalamic Pain

open access: yes康复学报, 2016
Objective:To observe the therapeutic effect of scalp acupuncture combined with transcutaneous electric nerve stimulation on treating thalamic pain.Methods:Sixty patients in thalamic hemorrhage associated with thalamic pain were assigned to the treatment ...
Xingyue FAN, Bo LIU, Weisong ZHANG
doaj  

Progress on responsive neurostimulation in treatment of drug⁃resistant epilepsy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Epilepsy is a common chronic neurological disorder that severely impacts the quality of life and social functioning. Approximately 1/3 of patients are diagnosed with drug⁃resistant epilepsy (DRE), for which conventional antiepileptic seizure medicine ...
FAN Xiu⁃liang   +3 more
doaj   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

open access: yesAdvanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou   +5 more
wiley   +1 more source

Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action. [PDF]

open access: yes, 2019
Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers an implantable, non-pharmacologic treatment for patients with intractable chronic pain conditions. Chronic pain is a widely heterogenous syndrome with regard to
Baker, Dewleen G   +12 more
core  

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

open access: yesAdvanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri   +4 more
wiley   +1 more source

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