Results 201 to 210 of about 273,359 (307)

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu   +7 more
wiley   +1 more source

Gold Nanorods in Cardiac Millitissues: Assessing Mechanical and Contractile Dynamics in a Living Engineering Myocardium Model

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a novel platform for assessing the active mechanical behavior of living cardiac microbundles through localized nanoindentation, integrated with temperature regulation and dual‐camera imaging systems. The developed system enables quantitative evaluation of dynamic micromechanics in engineered cardiac tissues in vitro, offering ...
Lihua Lou   +4 more
wiley   +1 more source

Prediction of clinical and language changes after a single session of repetitive transcranial magnetic stimulation in primary progressive aphasia: A machine learning approach. [PDF]

open access: yesJ Alzheimers Dis Rep
Rubio CM   +8 more
europepmc   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari   +2 more
wiley   +1 more source

Evaluating the electrical stimulation of bone cells based on an induced transmembrane potential model and intracellular calcium levels. [PDF]

open access: yesJ Tissue Eng
Bielfeldt M   +8 more
europepmc   +1 more source

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