Results 191 to 200 of about 1,235,726 (301)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Tribological behaviors of stator rubber with hexagonal micro-texture and enclosed groove of bionic honeycomb structure. [PDF]

iScience
Liu XF, Liu CH, Hou GX, Guo JY, Hao ZX, Shi XZ.   +5 more
europepmc   +1 more source

STRATIFIED ADAPTATION: Infrastructure, Elevation, and Cascading Floods in the Urban Mekong Delta

International Journal of Urban and Regional Research, EarlyView.
Abstract Flood‐prone cities in the global South are increasingly the target of infrastructure projects aimed at building climate ‘resilience’. At the same time, residents of these cities take adaptation to flooding into their own hands. In this article we examine the interrelationship between household‐scale and urban‐scale flood mitigation projects in
Lizzie Yarina, Vuong Kha Tu, Tran Kim Bao, Ly Quoc Dang   +3 more
wiley   +1 more source

Assessment of Groundwater Quality Using the Water Quality Index (WQI) in Woreillu Town, Ethiopia. [PDF]

Int J Anal Chem
Asfaw MD.
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Improving solar PV performance under bird-dropping conditions with a dual-cooling approach. [PDF]

Sci Rep
Ali KAM, Osman YKOT, El-Wahhab GGA, Abdelwahab TAM, Fodah AEM.   +4 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

A method for evaluating safety reliability of descend/ascend drop-weight system and mission abort decision for deep-ocean scientific human submersibles. [PDF]

Sci Rep
Palaniappan M, Bala Naga Jyothi V, Chowdhury T, Sathianarayanan D, Vedachalam N.   +4 more
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Comparative LCA of diesel and grid electricity for agricultural irrigation in Iran: why diesel outperforms in fossil-reliant grids. [PDF]

PLoS One
Namdari M.
europepmc   +1 more source