Results 161 to 170 of about 4,311 (249)

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

Advanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui, Neela K. Codadu, Daman Rathore, Guanghui Li, Marcello Meneghetti, Anders L. Bøcker, Rune W. Berg, Rob C. Wykes, Christos Markos   +8 more
wiley   +1 more source

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

Advanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos, Gustavo Felizardo Santos Sandes, Artur Christian Garcia da Silva, Holli‐Joi Martin, Eugene N. Muratov, Rodolpho de Campos Braga, Bruno Junior Neves   +6 more
wiley   +1 more source

Development of optimized ensemble machine learning-based prediction models for wire electrical discharge machining processes. [PDF]

Sci Rep
Sarker B, Chakraborty S, Čep R, Kalita K.   +3 more
europepmc   +1 more source

Recent Progress in Electrical Discharge Machining. Systematization of Electrical Discharge Machine.

Journal of the Japan Society for Precision Engineering, 1998
openaire   +2 more sources

From Design to Prototype: High‐Sensitivity Tri‐Mode Operation Photodetectors Based on 1T‐2H Hybrid MoS2

Advanced Science, EarlyView.
This work demonstrates a phase‐engineered MoS2 photodetector that dynamically switches among photocapacitive (PCC), photovoltaic (PV), and photoconductive (PC) modes. By transforming the traditionally parasitic capacitance into an active signal source, the device achieves self‐powered, high‐sensitivity detection with a fast response of 19.2 ms, and a ...
Xinyu Li, Daxiu Tang, Jiaxin Guo, Xiao Zhang, Sihan Liu, Yaojun Yu, Qianqian Cheng, Chengwei Gao, Xiaoning Guan, Pengfei Lu, Fei Zhuge, Ying Xie, Changgui Lin, Xiang Shen, Haohai Yu, Huaijin Zhang, Jiyang Wang   +16 more
wiley   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

The Influence of Contour Form Geometric Features and the Number of Cutting Passes on the Surface Quality Characteristics and Critical Points of Cutting Tools Fabricated by Wire Electrical Discharge Machining (WEDM). [PDF]

Micromachines (Basel)
Alinaghizadeh A, Azarhoushang B, Hadad M.   +2 more
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

An overview of techniques for monitoring and compensating tool wear in micro-electrical discharge machining. [PDF]

Heliyon
Nadda R, Nirala CK, Singh PK, Lee D, Kumar R, Singh T.   +5 more
europepmc   +1 more source