Results 81 to 90 of about 129,173 (308)

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell   +3 more
wiley   +1 more source

ACCURACY OF PATHOLOGIC Q WAVE ON ELECTROCARDIOGRAPHY TO PREDICT NON-VIABLE MYOCARDIUM

open access: diamond, 2023
Kashif Ali Hashmi   +4 more
openalex   +2 more sources

Efficacy and Safety of Dotinurad Versus Febuxostat for the Treatment of Gout: A Randomized, Multicenter, Double‐Blind, Phase 3 Trial in China

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicenter, randomized, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad ...
Jia Sun   +19 more
wiley   +1 more source

Angiographic findings in patients with conduction defect on resting electrocardiography [PDF]

open access: gold, 2022
Abdalameer Abd Al Bari   +2 more
openalex   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

Intravascular ultrasound evaluation of pulmonary hypertension in high-altitude patients with ventricular septal defect: a case report

open access: yesJournal of Medical Case Reports
Background High-altitude pulmonary hypertension is a rare but serious condition, particularly in individuals with congenital heart disease. Patent ductus arteriosus is a common congenital defect that may progress to irreversible pulmonary hypertension if
Yuanguo Chen   +4 more
doaj   +1 more source

Surface modification of textile electrodes to improve electrocardiography signals in wearable smart garment

open access: yesJournal of Materials Science: Materials in Electronics, 2019
Recording high quality biosignals by dry textile electrodes is a common challenge in medical health monitoring garments. The aim of this study was to improve skin–electrode interface and enhance the quality of recorded electrocardiography (ECG) signals ...
A. Soroudi   +3 more
semanticscholar   +1 more source

Percutaneous Management of Right Ventricular Outflow Tract Obstruction in an Adult Patient After Atrial Switch: A Case for Targeted Infundibular Ablation

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Alcohol septal ablation is a well‐established treatment method for patients with hypertrophic cardiomyopathy. We present a case report of a patient with transposition of the great arteries (TGA) after a Mustard procedure, who developed significant right ventricular outflow tract obstruction (RVOTO), functionally resembling subaortic stenosis ...
Vera Osberghaus   +6 more
wiley   +1 more source

Classification feasibility test on multi-lead electrocardiography signals generated from single-lead electrocardiography signals

open access: yesScientific Reports
Nowadays, Electrocardiogram (ECG) signals can be measured using wearable devices, such as smart watches. Most wearable devices provide only a few details; however, they have the advantage of recording data in real time. In this study, 12-lead ECG signals
Gi-Won Yoon, Segyeong Joo
doaj   +1 more source

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