Results 161 to 170 of about 48,655 (256)

Population Pharmacokinetic/Pharmacodynamic Modeling of Donidalorsen, an Antisense Oligonucleotide in Development for Prophylaxis of Hereditary Angioedema

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Hereditary angioedema (HAE) is a rare disorder linked to kallikrein‐kinin system dysregulation, which leads to uncontrolled activation of plasma prekallikrein. Donidalorsen is an antisense oligonucleotide designed to selectively degrade prekallikrein messenger RNA and thereby reduce prekallikrein production.
John K. Diep, Miao Liu, Pratap Singh, Steve Dorow, Danny M. Cohn, Laura Bordone, Kenneth B. Newman, Xiang Gao   +7 more
wiley   +1 more source

Sensitive immunosensing of melanoma biomarker based on enhanced electrochemiluminescence via electronic metal-support interactions. [PDF]

Front Chem
Pei J, Jia X, Xi F, Zhang B.
europepmc   +1 more source

Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice

Aging Cell, Volume 25, Issue 2, February 2026.
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang, Yu‐Jie Chen, Yu‐Xin Hu, Jia‐Chen Liu, Min Hu   +4 more
wiley   +1 more source

The Influence of Health Literacy on the Control of Hypothyroidism in Patients Under Levothyroxine Treatment

Clinical Endocrinology, Volume 104, Issue 2, Page 167-174, February 2026.
ABSTRACT Objective To investigate the association between health literacy levels and biochemical control of hypothyroidism, measured by serum TSH and free thyroxine (FT4) levels, in patients receiving levothyroxine (L‐T4) therapy. Methods We conducted a cross‐sectional study at the Thyroid Disorders Outpatient Clinic, Escola Paulista de Medicina ...
Jessyka Krause Meneses, Daniella Araujo Muniz, Débora Moroto, João Roberto Maciel Martins, Carolina Castro Porto Silva Janovsky   +4 more
wiley   +1 more source

Electrochemiluminescence Immunoassay [PDF]

, 2020
openaire   +1 more source

Testosterone threshold, assay and costs among laboratories for hypogonadism diagnosis. [PDF]

Transl Androl Urol
Gonzalez-Carranza HR, Morgentaler A, Reyes-Vallejo LA.   +2 more
europepmc   +1 more source

A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)

Clinical Endocrinology, Volume 104, Issue 2, Page 113-122, February 2026.
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea, Frédérique Lefrançois, Matthieu St‐Jean, Anne‐Marie Côté, Marie‐Ève Roy‐Lacroix, Mandy Malick, Pierre‐Luc Mallet, Nadine Sauvé   +7 more
wiley   +1 more source

Electrochemiluminescence Unit [PDF]

, 2020
openaire   +1 more source

Bright Circularly Polarized Electrochemiluminescence from Heterobinuclear Ir^III-Au^I Enantiomers. [PDF]

Angew Chem Int Ed Engl
Ballerini L, Liu M, Arrico L, Voci S, Gourlaouen C, Daniel C, César V, Bellemin-Laponnaz S, Zinna F, Bouffier L, Polo F, Di Bari L, Sojic N, Mauro M.   +13 more
europepmc   +1 more source

Endocrine Functions of Bone Are Suppressed by Orally Administered Glucose Regardless of Bodyweight

Clinical Endocrinology, Volume 104, Issue 2, Page 130-138, February 2026.
ABSTRACT Objective Bone is a target for diabetic complications, but the impact of metabolic changes on bone metabolism is less understood. Bones participate in energy metabolism by via secreted osteokines. Glucose ingestion reduces bone resorption, but the effects on osteokines remain unknown. Further, it is not known whether the response is altered in
Niki Jalava, Terhi J. Heino, Pirjo Nuutila, Kirsi A. Virtanen, Kaisa K. Ivaska   +4 more
wiley   +1 more source