Results 171 to 180 of about 49,306 (275)

Women with PCOS have a later menopausal transition and a lower prevalence of menopausal symptoms at age 46: A population‐based birth cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 836-846, May 2026.
Findings from a population‐based cohort study indicate that late peri−/postmenopausal status, as well as menopausal symptoms, were less prevalent in women with PCOS at age 46, supporting the hypothesis of prolonged ovarian function and a delayed menopausal transition with this condition. Created in https://BioRender.com.
Johanna Lavi   +6 more
wiley   +1 more source

Vessel‐associated microglia are differentially activated and distributed in relation to systemic infection and Alzheimer's disease

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
This post‐mortem study revealed an increased density of vessel‐associated microglia (VAM) in the temporal lobe in systemic infection and Alzheimer's disease. VAM density was related to brain cytokine levels and markers of cerebrovascular dysfunction and BBB leakage indicating that activated VAM contributes to neurovascular injury in Alzheimer's disease.
Oliver Milner   +5 more
wiley   +1 more source

From Microscale to Nanoscale Shadow Electrochemiluminescence Microscopy

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
In this research we report on the label‐free shadow electrochemiluminescence (shadow ECL) microscopy of microscale and nanoscale objects. By systematically investigating various influencing factors—including optical configuration, electrode activity, frame averaging, exposure time, and particle arrangement—we further confirm the nano‐imaging potential ...
Xiaodan Gou   +5 more
wiley   +2 more sources

Talquetamab: Mechanism of Action, Clinical, and Translational Science

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Talquetamab is a first‐in‐class, T‐cell–redirecting bispecific antibody targeting GPRC5D, a novel antigen highly expressed on malignant plasma cells with limited expression in normal tissues. Despite advances in treatment, multiple myeloma (MM) remains incurable, and talquetamab offers a promising therapeutic option for patients with relapsed ...
Yibo Wang   +10 more
wiley   +1 more source

The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi   +5 more
wiley   +2 more sources

Associations of High‐Sensitivity Cardiac Troponin and N‐Terminal Pro‐B‐Type Natriuretic Peptide With Echocardiographic Features in Patients With Hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 5, May 2026.
ABSTRACT High‐sensitivity cardiac troponin T (hs‐cTnT) and/or N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) levels are associated with left ventricular structure and function in general populations, however, evidence regarding their relationship with multidimensional echocardiographic features in patients with hypertension remains limited ...
Mingdan Wang   +11 more
wiley   +1 more source

Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 880-891, May 2026.
Serum levels of CTRP3 and CysC in elderly patients with T2DM and OP are closely associated with glucose‐lipid metabolism, bone mineral density, and bone metabolism markers. Combined detection of these two markers can assist in distinguishing OP in elderly patients with T2DM.
Yi‐Peng Wang   +4 more
wiley   +1 more source

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