Results 161 to 170 of about 49,306 (275)

Advanced Non‐Enzymatic Electrochemical Sensor Materials for Alzheimer's Disease Biomarkers

Analysis &Sensing, Volume 6, Issue 3, May 2026.
This review summarizes advances in materials‐driven, non‐enzymatic electrochemical biosensors for early Alzheimer's diagnosis via biofluid analysis. Amyloid‐β and hyperphosphorylated Tau are highlighted alongside sensor performance metrics, including sensitivity and selectivity.
Wei‐Ting Ting, Md Younus Ali, Claire Gage, Margaret Fahnestock, M. Firoz Mian, Matiar M. R. Howlader   +5 more
wiley   +1 more source

Spherical Nucleic Acid Stabilized Cage Type Three-Dimensional Electrochemiluminescence Probe for Sensitive and Amplification-Free Diagnosis of Infectious Diseases. [PDF]

Exploration (Beijing)
Fu Y, Song W, Lin J, Wang W, Liu L, Wu W, Yang H, Wang J, Yang Y, Shu B, Jiang Y, Liao Y.   +11 more
europepmc   +1 more source

Circulating Level of Growth‐Differentiation Factor 15 and Mortality of Patients With Acute Heart Failure: A Meta‐Analysis

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Elevated admission GDF‐15 levels are associated with increased mortality in acute heart failure. This meta‐analysis of 10 studies (N = 3724) found a pooled RR of 2.82 (95% CI: 2.39–3.32; p < 0.001; I² = 0%), supporting GDF‐15 as a promising biomarker for early risk stratification in AHF patients.
Pingkui Jin, Yanjie Geng, Erwei Huo, Yanhong Xue, Daofeng You, Qinghou Zheng   +5 more
wiley   +1 more source

An Enhanced Electrochemiluminescence Immunoassay Platform via Optimized Magnetic Bead Uniformity for Reliable Thyroid-Stimulating Hormone Monitoring. [PDF]

Bioengineering (Basel)
Lei H, Huang X, Cao X, Tang Y, Ge Y.
europepmc   +1 more source

Randomized Phase 1 Studies Evaluating the Safety, Tolerability, Pharmacokinetics, and Target Occupancy of Zampilimab in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 5, May 2026.
Abstract Zampilimab (UCB7858) is a humanized monoclonal immunoglobulin G4P, transglutaminase 2 (TG2) inhibiting antibody. We investigated safety, tolerability, pharmacokinetics, and target occupancy of zampilimab (intravenous ≤2000 mg; subcutaneous ≤1000 mg) in healthy participants in a randomized, placebo‑controlled, single‐ascending‐dose Phase 1 ...
Jo Collier, Rowann Bowcutt, Geoffrey I. Johnston, Jane Y. C. Chan, Anastasiia Raievska, Alison Bigley, Richard Nicholl, Tim S. Schmidt, Maria Sarno, Zahid Ali, Elizabeth Thomson   +10 more
wiley   +1 more source

Interference in thyroid function tests using the electrochemiluminescence immunoassay. [PDF]

Eur Thyroid J
Imamura C, Nishihara E, Fukata S, Ito M, Nishikawa M, Miyauchi A, Akamizu T.   +6 more
europepmc   +1 more source

Endogenous Recovery of Fasting C‐Peptide Decreases Progression of Sudomotor Small‐Fibre Dysfunction in Adults With Diabetes: A Real‐World Cohort Study

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
ABSTRACT Aims To determine whether recovery of fasting C‐peptide (ΔFCP) reduces deterioration in sudomotor small‐fibre function, whether a threshold exists, and whether associations are complication‐specific. Methods Retrospective real‐world cohort of 288 hospitalised adults with diabetes with repeated fasting C‐peptide and Sudoscan electrochemical ...
Qingyun Cai, Ting Xie, Hongjian Gong, Wenjie Zhang, Lixin Guo, Qi Pan   +5 more
wiley   +1 more source

Multidisciplinary cutting-edge technologies accelerating target-based drug discovery. [PDF]

J Pharm Anal
Li Y, Moaddel R, Jiang Z, Chen X.
europepmc   +1 more source

Population Pharmacokinetics of Trastuzumab Rezetecan in Patients With HER2‐Expressing or Mutated Advanced Solid Tumors

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Trastuzumab Rezetecan (SHR‐A1811) is an antibody‐drug conjugate (ADC) targeting the human epidermal growth factor receptor 2 (HER2). It features a novel enzyme‐cleavable linker and delivers the topoisomerase I inhibitor payload, rezetecan, with a drug‐to‐antibody ratio of approximately 6.0.
Xuehu Gao, Kaijing Zhao, Yanyong Zhao, Yanyan Zhang, Jun Zhao, Chen Zhao, Nassim Djebli   +6 more
wiley   +1 more source

Suspected Central Adrenal Insufficiency in a Patient with Phosphomannomutase 2-Congenital Disorder of Glycosylation. [PDF]

JCEM Case Rep
Ødum SF, Grønborg SW, Main KM, Klose M.   +3 more
europepmc   +1 more source