Results 41 to 50 of about 48,655 (256)

Electrochemiluminescence Microscopy

Angewandte Chemie
AbstractElectrochemiluminescence (ECL) is rapidly evolving from an analytical method into an optical microscopy. The orthogonality of the electrochemical trigger and the optical readout distinguishes it from classic microscopy and electrochemical techniques, owing to its near‐zero background, remarkable sensitivity, and absence of photobleaching and ...
Sara Knežević, Dongni Han, Baohong Liu, Dechen Jiang, Neso Sojic   +4 more
openaire   +2 more sources

Optimizing the Electrochemiluminescence of Readily Accessible Pyrido[1,2‐α]pyrimidines through “Green” Substituent Regulation

ChemElectroChem, 2021
Bright and low‐cost emitting organic molecules are very desirable for electrochemiluminescence (ECL). Here, we report a facile one‐step, three‐component reaction of readily available precursors to synthesize pyrido[1,2‐α]pyrimidine derivatives (1–4), all
Prof. Ruizhong Zhang, Jun Cheng, Liuqing Yang, Jonathan M. Wong, Jonathan Ralph Adsetts, Prof. Ruiyao Wang, Prof. Jiyan Liu, Prof. Zhifeng Ding, Prof. Hong‐Bo Wang   +8 more
doaj   +1 more source

Nanomaterials for Healthcare Biosensing Applications [PDF]

, 2019
In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field.
Altintas, Zeynep, Pirzada, Muqsit
core   +1 more source

Optical Bioassays Based on the Signal Amplification of Redox Cycling

Biosensors
Optical bioassays are challenged by the growing requirements of sensitivity and simplicity. Recent developments in the combination of redox cycling with different optical methods for signal amplification have proven to have tremendous potential for ...
Yunxiao Feng, Fengli Gao, Xinyao Yi, Ming La   +3 more
doaj   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Timescale correlation of shallow trap states increases electrochemiluminescence efficiency in carbon nitrides

Nature Communications
Highly efficient interconversion of different types of energy plays a crucial role in both science and technology. Among them, electrochemiluminescence, an emission of light excited by electrochemical reactions, has drawn attention as a powerful tool for
Yanfeng Fang, Hong Yang, Yuhua Hou, Wang Li, Yanfei Shen, Songqin Liu, Yuanjian Zhang   +6 more
doaj   +1 more source

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan, Alhosseini, Sanaz Naghavi, Rabiee, Mohammad, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +5 more
core   +1 more source

Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients. [PDF]

, 2019
BackgroundTuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine whether accurate TB antigen detection in blood or urine has the potential to meet the ...
Barbero, Simone, Bartlett, Daniel, Broger, Tobias, Denkinger, Claudia M, Katsuragi, Kiyonori, Kawasaki, Masanori, Lowary, Todd L, Mathew, Anu, Moreau, Emmanuel, Nahid, Payam, Pinter, Abraham, Plisova, Tatiana, Sigal, George B, Tsionksy, Michael   +13 more
core   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Biosensors Designed for Clinical Applications

Biomedicines, 2021
Emerging and validated biomarkers promise to revolutionize clinical practice, shifting the emphasis away from the management of chronic disease towards prevention, early diagnosis and early intervention.
James F. Rusling, Robert J. Forster
doaj   +1 more source