Results 61 to 70 of about 36,659 (288)

Porphyrin-Based Metal–Organic Frameworks for Efficient Electrochemiluminescent Chiral Recognition of Tyrosine Enantiomers

Chemosensors, 2022
Science the biological activities of chiral enantiomers are often different or even opposite, their chiral recognition is of great significance. A new assembly structure named TCPP-Zn-(S)-BINOL was obtained based on the interaction between chiral ...
Wen-Rong Cai, Wen-Kai Zhu, Bao-Zhu Yang, Da-Tong Wu, Jun-Yao Li, Zheng-Zhi Yin, Yong Kong   +6 more
doaj   +1 more source

Trends and Advances in Electrochemiluminescence Nanobiosensors [PDF]

Sensors, 2018
The rapid and increasing use of the nanomaterials (NMs), nanostructured materials (NSMs), metal nanoclusters (MNCs) or nanocomposites (NCs) in the development of electrochemiluminescence (ECL) nanobiosensors is a significant area of study for its massive potential in the practical application of nanobiosensor fabrication. Recently, NMs or NSMs (such as
Mohammad Rizwan, Noor Faizah Mohd-Naim, Minhaz Uddin Ahmed   +2 more
openaire   +3 more sources

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

An electrochemiluminescence assay for gp340 (DMBT1) [PDF]

Analytical Biochemistry, 2013
Gp340 is a member of the scavenger receptor cysteine-rich family of innate immune molecules and also functions as a tumor suppressor. This study describes a picogram-level assay using electrochemiluminescence technology on the MesoScale Discovery platform.
Cheryl, Barber, Drew, Weissman, Kurt, Barnhart, Minal, Dalvi, William R, Abrams, Daniel, Malamud   +5 more
openaire   +2 more sources

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Electrochemiluminescence and organic electronics of derivatised poly(aniline sulphonic acid) light-emitting diodes [PDF]

, 2011
>Magister Scientiae - MScApplications of electrochemiluminescent conjugated polymers offer promising solutions in addressing the problem of light emitting devices.
Molapo, Kerileng Mildred
core   +1 more source

A Novel Solid-State Electrochemiluminescence Sensor Based on poly(3-amino-4 hydroxybenzenesulfonic acid) /Ru(bpy)3 2+ Modified Electrode for Determination of Malachite Green

International Journal of Electrochemical Science, 2017
The poly(3-amino-4-hydroxybenzenesulfonic acid)/Ru(bpy)32+ modified glassy carbon electrode (PAHBS/Ru(bpy)32+/GCE) is a novel solid-state electrochemiluminescence (ECL) sensor.
Qiu-feng Lan, Wen-chang Wang, Xiao-hui Chen, Zhi-dong Chen   +3 more
doaj   +1 more source

Photoinduced Electrochemiluminescence Immunoassays

Analytical Chemistry
Optimization of electrochemiluminescence (ECL) immunoassays is highly beneficial for enhancing clinical diagnostics. A major challenge is the improvement of the operation conditions required for the bead-based immunoassays using the typical [Ru(bpy)3]2+/tri-n-propylamine (TPrA) system.
Dongni Han, Jasmina Vidic, Dechen Jiang, Gabriel Loget, Neso Sojic   +4 more
openaire   +4 more sources

Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients

Clinical Pharmacology &Therapeutics, EarlyView.
ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon, Tomomi Matsuura, Beata Holkova, Girish S. Gudi, Adam Drake, Maria Pihlgren, Piet H. van der Graaf, Sunitha GN, Andrew Garton, Mario Perro, Cyril Konto, Lida Pacaud   +11 more
wiley   +1 more source