Results 81 to 90 of about 49,306 (275)

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Fabrication and functionalization of PCB gold electrodes suitable for DNA-based electrochemical sensing [PDF]

, 2014
The request of high specificity and selectivity sensors suitable for mass production is a constant demand in medical research. For applications in point-of-care diagnostics and therapy, there is a high demand for low cost and rapid sensing platforms ...
Dhaenens, Kristof, Gielen, An, Henry, OYF, Lundeberg, J, O'Sullivan, CK, Salvo, Pietro, Sanchez, JLA, Solnestam, BW, Vanfleteren, Jan   +8 more
core   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Functionalizing Conductive Diamond: Recent Advance in Fabrication, Modifications, and Applications

Carbon Energy, EarlyView.
This review highlights recent advancements in the synthesis, modification, and electrochemical applications of conductive diamond, particularly boron‐doped diamond (BDD). It emphasizes progress in fabrication methods, including CVD and HPHT, and explores modifications such as doping, surface terminations, and composite design, enabling significant ...
Ning Linghu, Xin Jiang, Jing Xu
wiley   +1 more source

A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis. [PDF]

, 2018
The only currently commercialized point-of-care assay for tuberculosis (TB) that measures lipoarabinomannan (LAM) in urine (Alere LF-LAM) has insufficient sensitivity.
Broger, Tobias, Choudhary, Alok, Denkinger, Claudia M, Honnen, William J, Katsuragi, Kiyonori, Kawasaki, Masanori, Li, Andra, Lowary, Todd L, Mathew, Anu, Nahid, Payam, Pinter, Abraham, Plisova, Tatiana, Shen, Ke, Sigal, George B, Tsionsky, Michael, Zheng, Ruixiang Blake   +15 more
core  

Ground and excited state communication within a ruthenium containing benzimidazole metallopolymer [PDF]

, 2011
Emission spectroscopy and electrochemistry has been used to probe the electronic communication between adjacent metal centres and the conjugated backbone within a family of imidazole based metallopolymer, [Ru(bpy)2(PPyBBIM)n]2+, in the ground and excited
Blakely, Cameron, Cameron, Crawford, Dahms, Darren Griffith, Dennany, Dennany, Dennany, Dennany, Dennany, Dennany, Doherty, Emmet J. O'Reilly, Forster, Francois Moser, Haas, Hogan, Holiday, Jr. Arnold, Kaneko, Kasha, Keyes, Kingsborough, Kurashina, Lynn Dennany, Lyons, McClean, Mortimer, Nishihara, O'Mullane, Ofer, Osaheni, Paul, Rehm, Robert J. Forster, Roberts, Ruff, Shardon-Noblat, Terrill, Thackeray, Tia E. Keyes, Venkatanarayanan, Vogel, Wuelfing, Xing, Zhu, Ziessel   +47 more
core   +1 more source

Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao, Song Wang, Yuechao Yao, Yibo Dou   +3 more
wiley   +1 more source

On-line Mass Spectrometric Characterization of Key Intermediates in Luminol Electrochemiluminescence [PDF]

Zhipu Xuebao
Due to the low oxidation potential and high electrochemiluminescence (ECL) quantum yield, Luminol has been widely applied in analytical and detection fields, especially in immunoassay, food safety and environmental monitoring. However, there is a lack of
YU Kai1, QIAO Zhi-yuan1, ZHANG Ming-wang1, ZHU Qian-long1, LIU Ji-lin2, WANG Xue-ning1, YU Qian-yun1, JIANG Yan-xiao1, ZHANG Hong1, JIANG Jie1   +9 more
doaj   +1 more source

New materials for electrochemiluminescence [PDF]

, 2007
The study of electrochemiluminescence (ECL) involves photophysical and electrochemical aspects. Excited states are populated by an electrical stimulus. The most important applications are in the diagnostic field where a number of different biologically-relevant molecules (e.g.
openaire   +2 more sources

Dual‐Mode Electrophoretic Displays Enabled by Quantum Dot‐Decorated PR48:2 Pigment Particles and TiO2 for All‐Weather Visibility, Excellent Bistability, and Enhanced Readability

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a novel quantum dot electrophoretic display (QDEPD), which combines electro‐controlled reflection and optically‐triggered emission to achieve efficient multi‐modal switching within a single pixel. By incorporating multi‐component nanostructures, the system enhances functional integration and multi‐modal response capabilities.
Xingke Zheng, Yun Ye, Hongxing Xie, Yuanyi Liu, Ruihan Lin, Guangyou Liu, Tianyong Guan, Enguo Chen, Tailiang Guo   +8 more
wiley   +1 more source