Results 51 to 60 of about 48,655 (256)

Electrochemiluminescent detection of methamphetamine and amphetamine [PDF]

, 2016
Direct detection of amphetamine type stimulants (ATS) including methylamphetamine (MA) in street samples and biological matrices without the need for pretreatment or extraction is a great challenge for forensic drug analysis.
Dennany, Lynn, McGeehan, Jonathan
core   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Potential-Resolved Electrochemiluminescence and Its Application in Disease Biomarker Detection

Biosensors
Electrochemiluminescence (ECL) is a chemiluminescence phenomenon triggered by electrochemical reactions at the electrode surface, which has gradually become a high-sensitivity detection technology due to its low background, simple instrumentation, and ...
Liangbiao Wang, Xiaojing Su, Rongrong Han, Dexin Du, Mingquan Guo   +4 more
doaj   +1 more source

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1. [PDF]

, 2012
Observational studies suggest that host factors are associated with breast cancer risk. The influence of obesity, vitamin-D status, insulin resistance, inflammation, and elevated adipocytokines in women at high risk of breast cancer is unknown. The NSABP-
Amir, Eitan, Beddows, Samantha, Cecchini, Reena S, Costantino, Joseph P, Ganz, Patricia A, Goodwin, Pamela J, Hood, Nicola   +6 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Enhancement of Electrochemiluminescence by Au Paste Electrode for Bipolar Electroanalysis

Electrochemistry
Carbon paste electrodes (CPEs) are widely used because of their malleability and ease of modification of functional molecules. This study introduces the application of Au paste electrodes (AuPEs) as a method for amplifying electrochemiluminescence (ECL),
Ayane ENDO, Koki KUBOTA, Takahiro ITO-SASAKI, Mayo KOMATSU, Tomoki IWAMA, Hitoshi SHIKU, Kumi Y. INOUE   +6 more
doaj   +1 more source

Indium tin oxide overlayered waveguides for sensor applications [PDF]

, 1997
The use of indium tin oxide (ITO) thin films as electrodes for integrated optical electrochemical sensor devices is discussed. The effect of various thicknesses of ITO overlayers exhibiting low resistivity and high transparency on potassium ion-exchanged
Balasubramanian, Buchanan, Chung, Dobrowolski, Gnewuch, Heideman, Huber, Ingenhoff, Itoh, Kane, Kremeskötter, Lambeck, Latz, Lavers, Marantonio, Martinez, Maruyama, Miliou, Nason, Okamura, Piraud, Ross, Scholten, Sethi, Sloper, Weiss, Wilson, Woollam, Yao, Yip, Zhou   +30 more
core   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

2D Flower-like CdS@Co/Mo-MOF as Co-Reaction Accelerator of g-C₃N₄-Based Electrochemiluminescence Sensor for Chlorpromazine Hydrochloride

Biosensors
In this study, we have proposed an electrochemiluminescence (ECL) signal amplification system which is based on two-dimensional (2D) flower-like CdS@Co/Mo-MOF composites as a co-reaction accelerator of the g-C3N4/S2O82− system for ultrasensitive ...
Xiaowei Fan, Guping Zhang, Xiaodi Li, Yao Wang, Yi Wang, Shilei Hao, Defang Liu   +6 more
doaj   +1 more source

Sandwich-Type Electrochemiluminescence Immunosensor Based on CDs@dSiO₂ Nanoparticles as Nanoprobe and Co-Reactant

Biosensors, 2023
In general, co-reactants are essential in highly efficient electrochemiluminescence (ECL) systems. Traditional co-reactants are usually toxic, so it is necessary to develop new environmentally friendly co-reactants.
A-Ling Chen, Xiao-Yan Wang, Qing Zhang, Ning Bao, Shou-Nian Ding   +4 more
doaj   +1 more source