Results 11 to 20 of about 66,881 (155)

Clinical performance of the Roche Elecsys SARS-CoV-2 antigen fully automated electrochemiluminescence immunoassay

open access: yesPractical Laboratory Medicine, 2022
Objective: We assessed the clinical performance of novel Roche Elecsys SARS-CoV-2 Antigen fully automated electrochemiluminescence immunoassay (ECLIA). Design and methods: We tested 160 subjects, 110 (68.8%), with positive molecular test for SARS-CoV-2 ...
Gian Luca Salvagno   +3 more
doaj   +2 more sources

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications [PDF]

open access: yesAGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +2 more sources

Comparison of chemiluminescence enzyme immunoassay based on magnetic microparticles with traditional colorimetric ELISA for the detection of serum α-fetoprotein

open access: yesJournal of Pharmaceutical Analysis, 2012
A chemiluminescence enzyme immunoassay based on magnetic microparticles (MmPs-CLEIA) was developed to evaluate serum α-fetoprotein (AFP) in parallel with traditional colorimetric enzyme-linked immunosorbent assay (ELISA). A systematic comparison between
Qian-Yun Zhang   +3 more
doaj   +2 more sources

Comparison between a rapid diagnostic test and dried blood spot-based immunoassay for hepatitis B surface antigen testing: Performance and cost implications in a population-based serosurvey in Vietnam

open access: yesInternational Journal of Infectious Diseases, 2022
Objectives: This study aimed to determine the agreement between a rapid diagnostic test (RDT) and a dried blood spot (DBS)-based electrochemiluminescence immunoassay (ECLIA) of hepatitis B surface antigen and to compare the costs of conducting ...
Sumiyo Okawa   +17 more
doaj   +2 more sources

Sugammadex interference with serum progesterone measurement: an in‐vitro study [PDF]

open access: yesAnaesthesia, Volume 81, Issue 11, Page 1489-1496, November 2026.
Summary Introduction Sugammadex may interfere with serum progesterone immunoassays, potentially rendering measured concentrations and resulting recommendations unreliable. Methods We investigated the effect of a range of sugammadex concentrations on serum progesterone concentrations in samples from pre‐menopausal female volunteers.
Tamblyn Devoy   +5 more
wiley   +2 more sources

Comparative Analytical Performance and Clinical Agreement of Chemiluminescence Microparticle Immunoassay and Electrochemiluminescence Immunoassay for CA19-9: A Diagnostic Accuracy Study [PDF]

open access: yesDiagnostics
Background: Carbohydrate antigen 19-9 (CA19-9) is widely used as a tumor marker for pancreatic and hepatobiliary malignancies. However, inter-assay variability may affect the interpretation of results.
Jongkonnee Wongpiyabovorn   +2 more
doaj   +2 more sources

Serum Neurofilament Light Chain and GFAP in Amyotrophic Lateral Sclerosis on a Commercial ECLIA Platform [PDF]

open access: yesMuscle &Nerve, Volume 74, Issue 5, Page 1398-1405, November 2026.
ABSTRACT Introduction/Aims In amyotrophic lateral sclerosis (ALS), SIMOA‐based studies show that baseline serum neurofilament light chain (NfL) predicts the revised ALS Functional Rating Scale (ALSFRS‐R) decline rate and survival. The Roche Elecsys electrochemiluminescence immunoassay (ECLIA) reports values approximately six‐fold lower; cross‐platform ...
Nicholas S. Streicher
wiley   +2 more sources

Comparative Evaluation and Measure of Accuracy of ELISAs, CLIAs, and ECLIAs for the Detection of HIV Infection among Blood Donors in China

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2020
Background. Enzyme-linked immunosorbent assay (ELISA) is the only serological method approved for blood screening in China. Automated chemiluminescence immunoassay (CLIA) and electrochemiluminescence immunoassay (ECLIA) had been used in clinical ...
Le Chang   +6 more
doaj   +2 more sources

An Enhanced Electrochemiluminescence Immunoassay Platform via Optimized Magnetic Bead Uniformity for Reliable Thyroid-Stimulating Hormone Monitoring [PDF]

open access: yesBioengineering
Electrochemiluminescence immunoassay (ECLIA) is widely used in clinical diagnostics owing to its high sensitivity, broad dynamic range, and excellent analytical stability.
Hengbo Lei   +4 more
doaj   +2 more sources

Development and validation of a multiplex electrochemiluminescence immunoassay to evaluate dry eye disease in rat tear fluids

open access: yesScientific Reports, 2023
Dry eye disease (DED) is a challenge in ophthalmology. Rat models represent valuable tools to study the pathophysiology and to develop novel treatments.
Agnese Compagnone   +3 more
doaj   +3 more sources

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