Results 21 to 30 of about 9,221 (208)

Neuroprotective Effect of Lercanidipine- A Novel Calcium Channel Blocker in Albino Mice [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: The available conventional antiepileptics do not afford cure or prophylactic treatment and henceforth there is always a quest to explore new targets for management of convulsions.
Nitya Selvaraj, Mangaiarkkarasi Adhimoolam, Deepa Kameswari Perumal, Meher Ali Rajamohammed   +3 more
doaj   +1 more source

Ryanodine receptors are involved in the improvement of depression-like behaviors through electroconvulsive shock in stressed mice

Brain Stimulation, 2021
Background: Electroconvulsive therapy (ECT) is effective for treating depression. However, the mechanisms underlying the antidepressant effects of ECT remain unknown. Depressed patients exhibit abnormal Ca2+ kinetics.
Emi Nakamura-Maruyama, Risa Kai, Naoyuki Himi, Naohiko Okabe, Kazuhiko Narita, Tetsuji Miyazaki, Shozo Aoki, Osamu Miyamoto   +7 more
doaj   +1 more source

Antiamnestic effect of new nicotinic acid derivatives [PDF]

Research Results in Pharmacology, 2021
Introduction: The search for new drugs for the prevention and treatment of vascular cognitive disorders continues to be a relevant task of pharmacology.
Victor V. Yasnetsov, Diana E. Kaurova, Sofia Ya. Skachilova, Evgeniy Yu. Bersenev   +3 more
doaj   +3 more sources

Seizure-Induced Arc mRNA Expression Thresholds in Rat Hippocampus and Perirhinal Cortex

Frontiers in Systems Neuroscience, 2018
Immediate-early genes (IEGs) are rapidly and transiently induced following excitatory neuronal activity including maximal electroconvulsive shock treatment (ECT).
Monica K. Chawla, Monica K. Chawla, Daniel T. Gray, Daniel T. Gray, Christie Nguyen, Christie Nguyen, Harshaan Dhaliwal, Harshaan Dhaliwal, Marc Zempare, Marc Zempare, Hiroyuki Okuno, Matthew J. Huentelman, Matthew J. Huentelman, Carol A. Barnes, Carol A. Barnes, Carol A. Barnes   +15 more
doaj   +1 more source

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María, Borges, Gisela, Micó Segura, Juan Antonio, Neto, Fani L., Torres-Sanchez, Sonia   +4 more
core   +4 more sources

Care, control and the electroconvulsive therapy (ECT) ritual: Making sense of polarised patient narratives [PDF]

, 2017
Despite evidence of short-term effectiveness of ECT (electroconvulsive therapy), both positive and negative patient reports are common. However, research examining these polarized accounts has not adequately elucidated why such divergences occur. We thus
Griffith, L., Griffith, L., Knight, F., Knight, F., McShane, R., McShane, R., Ridge, Damien T., Ridge, Damien T., Ryan, S., Ryan, S.   +9 more
core   +1 more source

Failure of Repeated Electroconvulsive Shock Treatment on 5-HT4-Receptor-Mediated Depolarization Due To Protein Kinase A System in Young Rat Hippocampal CA1 Neurons

Journal of Pharmacological Sciences, 2004
We previously demonstrated that repeated electroconvulsive shock (ECS) treatment enhanced serotonin (5-HT)1A- and 5-HT3-receptor-mediated responses in hippocampal CA1 pyramidal neurons.
Kumatoshi Ishihara, Masashi Sasa
doaj   +1 more source

Bilateral Asymmetrical Fracture Dislocation of Shoulder with Rare Combination of Injuries after Epileptic Seizure: A Case Report [PDF]

Malaysian Orthopaedic Journal, 2017
The incidence of bilateral gleno-humeral joint dislocation is rare, is almost always posterior and is usually caused by sports injuries, epileptic seizures, electrical shock, or electroconvulsive therapy.
Sharma A, Jindal S, Narula MS, Garg S, Sethi A   +4 more
doaj   +1 more source

Neuronal activity regulates hippocampal miRNA expression. [PDF]

PLoS ONE, 2011
Neuronal activity regulates a broad range of processes in the hippocampus, including the precise regulation of translation. Disruptions in proper translational control in the nervous system are associated with a variety of disorders that fall in the ...
Stephen M Eacker, Matthew J Keuss, Eugene Berezikov, Valina L Dawson, Ted M Dawson   +4 more
doaj   +1 more source

Non-convulsive epiletic seizure after electroconvulsive therapy session

European Psychiatry, 2023
Introduction Electroconvulsive therapy (ECT) is a procedure performed under general anaesthesia involving triggering an intentional brief seizure through small electrical currents through the brain.
L. Llovera García, L. Veiga Gil, L. Lopez Unzue, A. Corrales Rodriguez, A. Ballesteros Prados, J. Yoldi Murillo, J. M. Lopez Ilundain   +6 more
doaj   +1 more source