Results 51 to 60 of about 2,365,238 (239)
BackgroundMajor depressive disorder is among the most disabling illnesses worldwide, with a lifetime prevalence of 16.2%. Research suggests that 20% to 40% of patients with depression do not respond to pharmacotherapy, developing ...
Yuliya Knyahnytska +5 more
doaj +1 more source
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota +14 more
wiley +1 more source
Joint Risk Factor Combinations with Additive Interaction Increase the Risk of Parkinson's Disease
Abstract Background Combined effects of multiple risk factors on incident late‐onset Parkinson's disease (PD; LOPD) remain poorly characterized. Objective The objective of this study was to quantify the impact of joint risk exposures and estimate the contribution of potentially modifiable factors to incident LOPD risk.
Andrea Quattrone +5 more
wiley +1 more source
Care, control and the electroconvulsive therapy (ECT) ritual: Making sense of polarised patient narratives [PDF]
Despite evidence of short-term effectiveness of ECT (electroconvulsive therapy), both positive and negative patient reports are common. However, research examining these polarized accounts has not adequately elucidated why such divergences occur. We thus
Knight, F. +4 more
core +1 more source
Background: Clinical practice protocols should consider both the psychological criteria related to a patient’s satisfaction as a consumer of health services and the economic criteria to allocate resources efficiently. An electroconvulsive therapy program
Carmen Selva- Sevilla +2 more
doaj +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source
ABSTRACT Introduction Understanding the differences in treatment response between subtypes of major depressive disorder (MDD) may help to prevent lengthy trial‐and‐error processes by identifying effective treatment options. The aim of the study was to investigate the impact of atypical features of MDD (MDD‐A) on the response to lithium augmentation (LA)
Hannah Buchbauer +8 more
wiley +1 more source
Validation of the Catatonia Quick Screen in the Original Bush‐Francis Catatonia Rating Scale Cohort
ABSTRACT Introduction Delayed catatonia diagnosis may cause preventable harm. The 4‐item Catatonia Quick Screen (CQS) allows rapid screening, but its specificity requires evaluation. We assessed CQS sensitivity and specificity using the original Bush Francis Catatonia Rating Scale (BFCRS) cohort.
James Luccarelli +6 more
wiley +1 more source
Patients Receiving 100 or More Electroconvulsive Therapy Treatments in a Nationwide Cohort
ABSTRACT Introduction Very high cumulative exposure to electroconvulsive therapy (ECT) has primarily been described in individual case reports. We examined cumulative ECT exposure in a nationwide Japanese claims database to characterize patients receiving very high numbers of treatments.
Masahiro Hata +2 more
wiley +1 more source
Electrocardiographic and Blood Pressure Alterations During Electroconvulsive Therapy in Young Adults
OBJECTIVE - To study cardiovascular alterations in young patients with no apparent organic disease who underwent electroconvulsive therapy. METHODS - The study comprised 47 healthy patients (22 males and 25 females) with a mean age of 30.3 years, who ...
Rumi Demetrio Ortega +7 more
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