Results 171 to 180 of about 20,949 (259)

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan   +10 more
wiley   +1 more source

Electroencephalography functional connectivity—A biomarker for painful polyneuropathy

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 204-214, January 2023., 2023
Abstract Background and purpose Advanced analysis of electroencephalography (EEG) data has become an essential tool in brain research. Based solely on resting state EEG signals, a data‐driven, predictive and explanatory approach is presented to discriminate painful from non‐painful diabetic polyneuropathy (DPN) patients.
Leah Shafran Topaz   +17 more
wiley   +1 more source

Drug‐resistant epilepsy and mortality—Why and when do neuromodulation and epilepsy surgery reduce overall mortality

open access: yesEpilepsia, Volume 63, Issue 12, Page 3020-3036, December 2022., 2022
Abstract Patients with drug‐resistant epilepsy have an increased mortality rate, with the majority of deaths being epilepsy related and 40% due to sudden unexpected death in epilepsy (SUDEP). The impact of epilepsy surgery on mortality has been investigated since the 1970s, with increased interest in this field during the past 15 years.
Sylvain Rheims   +2 more
wiley   +1 more source

Successful treatment of adult Dravet syndrome patients with cenobamate

open access: yesEpilepsia, Volume 63, Issue 12, Page e164-e171, December 2022., 2022
Abstract Dravet syndrome (DS) is a rare, drug‐resistant, severe developmental and epileptic encephalopathy caused by pathogenic variants in the α subunit of the voltage‐gated sodium channel gene SCN1A. Hyperexcitability in DS results from loss of function in inhibitory interneurons.
Konstantin L. Makridis   +6 more
wiley   +1 more source

Benign Idiopathic Myoclonus: A New Clinical Entity?

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus is a brief shock‐like, involuntary movement, which can be distinguished in physiologic, essential, epileptic, and symptomatic, according to its etiology. Physiologic myoclonus typically occurs in healthy people without disability or progression.
Giorgia Sciacca   +6 more
wiley   +1 more source

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