Results 191 to 200 of about 141,484 (301)

Artificial intelligence‐assisted detection of epileptic spasms using electroencephalographic–video analysis

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate an artificial intelligence (AI) diagnostic tool using hybrid electroencephalographic (EEG)–video signals for automatic epileptic spasms (ES) detection. Methods This retrospective cohort study with internal cross‐validation and multicenter external validation was conducted from July ...
Lin Wan, Nan Lin, Wen Wang, Zi Liang, Yisu Dong, Haibo He, Jian Chen, Yuying Fan, Tong Liu, Hongjie Wang, Weike Cheng, Guangshuang Lu, Juan Wang, Bo Zhang, Qiang Lu, Guang Yang   +15 more
wiley   +1 more source

Thalamic connectivity mirrors spatial maps of network dysfunction in nonlesional focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Focal epilepsy is increasingly conceptualized as a network disorder, yet the extent to which network dysfunction reflects a shared phenotype remains unknown. Spatially conserved patterns of network dysfunction may implicate a centralized mechanism underlying widespread impairment.
Joline M. Fan, Ehsan Tadayon, Kiwamu Kudo, Kamalini G. Ranasinghe, Anne M. Findlay, Robert C. Knowlton, Vikram R. Rao, Srikantan S. Nagarajan   +7 more
wiley   +1 more source

Focal seizures during simulated driving: A pilot study

Epilepsia, EarlyView.
Abstract Cars are increasingly equipped with technology that can be used to analyze driver behavior and alertness, often referred to as driver monitoring systems (DMS). Although initially mainly used to track drivers' attention, DMS are now expanding in the hope of detecting additional forms of driver impairment that may jeopardize driving, such as ...
Emma Nilsson, Mirta Zelenika Zeba, Joakim Strandberg, Peter Lundgren, Johan Zelano   +4 more
wiley   +1 more source

Agreement and 2‐year trajectories of youth‐ and parent‐reported health‐related quality of life in youth with epilepsy treated with surgery vs medical therapy

Epilepsia, EarlyView.
Abstract Objective This cohort study examined the agreement between youth‐ and parent‐reported health‐related quality of life (HRQOL) of children treated with epilepsy surgery compared to medical therapy. A second aim was to evaluate whether changes in HRQOL over 2 years differed between the two groups, and to determine whether these trajectories ...
Mary Lou Smith, Klajdi Puka, Elysa Widjaja   +2 more
wiley   +1 more source

Recommendations for structural magnetic resonance imaging in infants with first afebrile seizure or new onset epilepsy: Evidence‐based recommendations from the ILAE Neuroimaging Task Force

Epilepsia, EarlyView.
Abstract Infants aged 1–24 months with new onset epilepsy frequently present with structural brain abnormalities, yet no updated evidence‐based magnetic resonance imaging (MRI) guidelines exist for this population. The International League Against Epilepsy (ILAE) Neuroimaging Task Force developed evidence‐based recommendations for structural brain MRI ...
Gavin P. Winston, Simone Salemme, Gaetano Cantalupo, Fernando Cendes, Felice D′Arco, Paolo Federico, William D. Gaillard, Eliane Kobayashi, Edward J. Novotny, Godwin Ogbole, Abdul Kareem Pullattayil, Domenico Tortora, Matthew T. Whitehead, Taoyun Yi, Francesco Brigo, Anna Elisabetta Vaudano   +15 more
wiley   +1 more source

Performance of the 5‐SENSE score in a pediatric and young adult cohort of 100 consecutive stereoelectroencephalography cases

Epilepsia, EarlyView.
Abstract This study assesses the validity of the 5‐SENSE score in a cohort of pediatric patients with epilepsy and evaluates associations between the score, ancillary testing, and surgical outcomes. We retrospectively calculated the 5‐SENSE score in a single‐center predominantly pediatric cohort and calculated the sensitivity and specificity for ...
Lindsey Trank, Amanda R. B. Weber, Christopher Beatty, Gabrielle Brown‐Mitchell, Mariah Eisner, Jonathan Pindrik, Ammar Shaikhouni, Adam Ostendorf   +7 more
wiley   +1 more source

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini, Eric D. Marsh, Wei‐Ping Liao, Katsumi Imai, Ruzica Kravljanac, Anna Altmann, Cecil D. Hahn, Stéphane Auvin, Jimmy Schiemann, Yasir Khan, Pranab Mitra, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Dennis Dlugos, Venkatesha Murthy   +15 more
wiley   +1 more source

Intracranial electroencephalographic approaches in the intensive care unit: Safety, feasibility, and coverage

Epilepsia, EarlyView.
Abstract Objective Nonconvulsive epileptic activity is common after acute brain injury and contributes to neuronal injury and poor outcomes. Although intracranial electroencephalography (iEEG) improves detection compared with surface EEG (suEEG), it currently relies on focal recordings of epileptic dynamics.
Steven Smeijers, Mariella Segreti, Anaïs Van Hoylandt, Jeroen Gijs, Johannes van Loon, Lauranne Scheldeman, Bart Depreitere, Tom Theys   +7 more
wiley   +1 more source

The Clinical Significance of Abnormal Electroencephalography (EEG) Patterns in Patients with Neuropsychiatric Disorders Due to Anti-NMDA Receptor Encephalitis: A Comparative Study. [PDF]

Diagnostics (Basel)
Moreno-Avellán A, Juarez-Jaramillo A, Fernandez Gonzalez-Aragon MDC, Quiñones-Pesqueira G, Pineda-Centeno LM, Espinola-Nadurille M, Martinez-Angeles V, Martinez-Carrillo F, Rivas-Alonso V, San-Juan D, Flores-Rivera J, Ramirez-Bermudez J.   +11 more
europepmc   +1 more source

Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie, Arianna Damiani, Mahsa Khoshkhou, Luis A. Sanchez, Rachel J. Smith, Shruti H. Agashe, Jorge A. Gonzalez‐Martinez, Jennifer Hopp, Adam S. Charles, Sridevi V. Sarma, Joon‐Yi Kang   +10 more
wiley   +1 more source