Results 91 to 100 of about 5,038,245 (370)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Mathematical Modeling of Uranium Neutron-Producing Target of Subcritical Assembly NSC KIPT

open access: yesEast European Journal of Physics
This work is devoted to calculating the rate of radiation damage production in a uranium target irradiated with high-energy electrons with an energy of 100 MeV.
V.V. Gann   +4 more
doaj   +1 more source

Spectral properties of a broadband far infrared photodetector with a new design of active region

open access: yesCondensed Matter Physics, 2023
A quantum theory of spectral parameters and oscillator strengths of quantum transitions in an active region, which contains cascades of wide quantum wells with a complicated potential profile is developed.
M. V. Tkach   +3 more
doaj   +1 more source

Generalized gradient approximation for the exchange-correlation hole of a many-electron system.

open access: yesPhysical Review B (Condensed Matter), 1996
We construct a generalized gradient approximation (GGA) for the density ${\mathit{n}}_{\mathrm{xc}}$(r,r+u) at position r+u of the exchange-correlation hole surrounding an electron at r, or more precisely for its system and spherical average 〈${\mathit{n}
J. Perdew, K. Burke, Yue Wang
semanticscholar   +1 more source

Density-functional method for nonequilibrium electron transport [PDF]

open access: yes, 2001
We describe an ab initio method for calculating the electronic structure, electronic transport, and forces acting on the atoms, for atomic scale systems connected to semi-infinite electrodes and with an applied voltage bias.
M. Brandbyge   +4 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

ДОСЛІДЖЕННЯ ВПЛИВУ ХАОТИЧНОГО СТРУМУ ЕЛЕКТРОНІВ НА ПАРАМЕТРИ ЕЛЕКТРИЧНОГО ПОЛЯ У ПРИАНОДНІЙ ЗОНІ РОЗРЯДУ

open access: yesElektrotehnìka ta Elektroenergetika, 2010
Розглянуто вплив співвідношення густини розрядного та хаотичного електронних струмів на падіння потенціалу у дифузійній зоні прианодної області. Виконано аналіз впливу вимушеної конвекції на умови існування стійкого дифузного розряду на поверхні анода.
A. V. Ershov, G. I. Camel, I. M. Kotsur
doaj   +1 more source

Electron-Electron Interactions in Artificial Graphene

open access: yesPhysical Review Letters, 2012
Recent advances in the creation and modulation of graphene-like systems are introducing a science of "designer Dirac materials". In its original definition, artificial graphene is a man-made nanostructure that consists of identical potential wells (quantum dots) arranged in a adjustable honeycomb lattice in the two-dimensional electron gas.
Stefano Pittalis   +5 more
openaire   +5 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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