Results 91 to 100 of about 8,209,944 (376)

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

International Journal of Molecular Medicine, 2019
The mammalian mitochondrial electron transport chain (ETC) includes complexes I-IV, as well as the electron transporters ubiquinone and cytochrome c. There are two electron transport pathways in the ETC: Complex I/III/IV, with NADH as the substrate and ...
Ruzhou Zhao, Shuai Jiang, Lin Zhang, Zhi-Bin Yu   +3 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Impact of Electron-Electron Cusp on Configuration Interaction Energies

, 2001
The effect of the electron-electron cusp on the convergence of configuration interaction (CI) wave functions is examined. By analogy with the pseudopotential approach for electron-ion interactions, an effective electron-electron interaction is developed ...
Fahy, Stephen, Filippi, Claudia, Greer, J. C., Nolan, M., Prendergast, David   +4 more
core   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Electron correlation energy in confined two-electron systems

, 2010
Radial, angular and total correlation energies are calculated for four two-electron systems with atomic numbers Z=0-3 confined within an impenetrable sphere of radius R.
Aquino, Aquino, C.L. Wilson, D.C. Thompson, Ezra, Ezra, Flores-Riveros, Gell-Mann, Gilbert, Gimarc, Green, H.E. Montgomery, Hohenberg, Huang, Hylleraas, Jung, K.D. Sen, Kais, Kestner, Koga, Koga, Kohn, Loos, Loos, Loos, Löwdin, Montgomery, Pan, Saito, Saito, Taylor, ten Seldam, Tew, Thompson, Thompson, Umrigar, Wigner   +36 more
core   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Charged particle single nanometre manufacturing

Beilstein Journal of Nanotechnology, 2018
Following a brief historical summary of the way in which electron beam lithography developed out of the scanning electron microscope, three state-of-the-art charged-particle beam nanopatterning technologies are considered. All three have been the subject
Philip D. Prewett, Cornelis W. Hagen, Claudia Lenk, Steve Lenk, Marcus Kaestner, Tzvetan Ivanov, Ahmad Ahmad, Ivo W. Rangelow, Xiaoqing Shi, Stuart A. Boden, Alex P. G. Robinson, Dongxu Yang, Sangeetha Hari, Marijke Scotuzzi, Ejaz Huq   +14 more
doaj   +1 more source

Kohn anomaly and interplay of electron-electron and electron-phonon interactions in epitaxial graphene

, 2008
The interplay of electron-phonon (el-ph) and electron-electron (el-el) interactions in epitaxial graphene is studied by directly probing its electronic structure.
A. Bostwick, A. Lanzara, A. V. Fedorov, D. A. Siegel, N. W. Ashcroft, S. Y. Zhou   +5 more
core   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Laser-Wakefield Electron Beams as Drivers of High-Quality Positron Beams and Inverse-Compton-Scattered Photon Beams

Frontiers in Physics, 2019
The fast-paced development of laser-wakefield electron acceleration has recently culminated in the generation of electron beams with extreme characteristics, including femtosecond-scale duration, mrad divergence, and high-energy.
Aaron Alejo, Guillermo M. Samarin, Jonathan R. Warwick, Gianluca Sarri   +3 more
doaj   +1 more source