Results 41 to 50 of about 5,052,753 (344)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

A semiclassical approach reproducing asymptotically the Heitler formula for atomic photoionization

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2020
The wave-corpuscle method for description of atomic photoionization by a flux of photons in the visible and X-ray range was developed and applied. Using the calculated photoionization probability in the asymptotics, we obtained the desired approximate ...
A.M. Shaimardanov   +2 more
doaj   +1 more source

Basic concept and application of conducting polymers for environmental protection

open access: yesChemistry Teacher International, 2022
Recently, the importance of sustainable environment has been engaged in many science practices and learning. This article intends to provide teachers in secondary school and research beginners with knowledge background on conducting polymers (CPs) for ...
Baharin Siti Nor Atika   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ultrastructural transneuronal degeneration study of axonal elements within the paratrigeminal nucleus in sinoaortic deafferented rats [PDF]

open access: yesEinstein (São Paulo), 2012
Objective: Morphological study that searched to authenticate thepresence of sinoaortic baroreceptor inputs within the dorsolateralmedullary nucleus under electron microscopy analysis.
Cristofer André Caous   +3 more
doaj  

Robust and adjustable C-shaped electron vortex beams

open access: yesNew Journal of Physics, 2017
Wavefront engineering is an important quantum technology, often applied to the production of states carrying orbital angular momentum (OAM). Here, we demonstrate the design and production of robust C-shaped beam states carrying OAM, in which the usual ...
M Mousley   +3 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Tumor bed boost in breast cancer: Brachytherapy versus electron beam

open access: yesIndian Journal of Medical and Paediatric Oncology, 2013
Background: The prospective study aimed to evaluate the effectiveness of Electron beam or HDR 192Ir Interstitial Implant used as a boost in breast Conservation cases after completion of EBRT.
Sanjoy Roy   +5 more
doaj   +1 more source

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