Results 71 to 80 of about 5,521,327 (281)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Data transmission by quantum matter wave modulation

New Journal of Physics, 2021
Classical communication schemes exploiting wave modulation are the basis of our information era. Quantum information techniques with photons enable future secure data transfer in the dawn of decoding quantum computers.
R Röpke, N Kerker, A Stibor
doaj   +1 more source

The role of electron-electron scattering in spin transport

, 2010
We investigate spin transport in quasi 2DEG formed by III-V semiconductor heterojunctions using the Monte Carlo method. The results obtained with and without electron-electron scattering are compared and appreciable difference between the two is found ...
Akashdeep Kamra, Bahniman Ghosh, Bandyopadhyay S., Brooks H., Datta S., D’yakonov M. I., Fischetti M. V., Pikus G. E., Tierney B. D.   +8 more
core   +1 more source

Modeling Radiation Belt Electrons With Information Theory Informed Neural Networks [PDF]

, 2022
S. Wing, D. L. Turner, A. Y. Ukhorskiy, J. R. Johnson, T. Sotirelis, Romina Nikoukar, G. Romeo   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Analysis of the mineral composition of hypomineralized first permanent molars [PDF]

Vojnosanitetski Pregled, 2015
Background/Aim. Hypomineralization of molars and incisors (molar-incisor hypomineralization - MIH) is defined as enamel hypomineralization of systemic origin of one or more of the four first permanent molars, which may be associated with changes
Martinović Brankica, Ivanović Mirjana, Milojković Zoraida, Mladenović Raša   +3 more
doaj   +1 more source

Effect of Strongly Magnetized Electrons and Ions on Heat Flow and Symmetry of Inertial Fusion Implosions [PDF]

, 2022
A. Bose, J. Peebles, C. A. Walsh, J. A. Frenje, N. V. Kabadi, P. J. Adrian, G. D. Sutcliffe, M. Gatu Johnson, C. A. Frank, J. R. Davies, R. Betti, V. Yu. Glebov, Fred Marshall, S. P. Regan, C. Stöeckl, E. M. Campbell, H. Sio, J D Moody, Aidan Crilly, Brian Appelbe, J. P. Chittenden, S. Atzeni, F. Barbato, Alessandro Forte, C. K. Li, F. H. Séguin, R. D. Petrasso   +26 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Electron-Electron Bremsstrahlung Emission and the Inference of Electron Flux Spectra in Solar Flares

, 2007
Although both electron-ion and electron-electron bremsstrahlung contribute to the hard X-ray emission from solar flares, the latter is normally ignored.
A. Gordon Emslie, Anna Maria Massone, Eduard P. Kontar, Haug E., Haug E., John C. Brown, Marco Prato, Michele Piana, Trottet G.   +8 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source