Results 111 to 120 of about 4,690,653 (292)
Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]
, 2006 Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David +23 more
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Electron density and packing effects
, 1995 C. Gatti: 'Electron density and packing effects', invited plenary lecture alla Gordon Conference on Electron Distribution and Chemical Bonding, Plymouth State College, N.
Gatti Carlo
core
A Computer Study of Electron-Electron Interaction in high Density Electron Beams [PDF]
, 1979 High density electron beams are simulated by a computer, and the trajectory displacement and energy broadening caused by electron-electron interaction are investigated computationally.
Sasaki, Tateaki
core
Bond orders in metal–metal interactions through electron density analysis
, 2011 The metal–metal bond is central in the chemistry of polymetallic complexes. Many structural investigations, both experimental and theoretical, have been carried out with the purpose of understanding this interaction in more detail and of being able to ...
Macchi, P. +3 more
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
PyIRI: Whole‐Globe Approach to the International Reference Ionosphere Modeling Implemented in Python
Space WeatherThe International Reference Ionosphere (IRI) model is widely used in the ionospheric community and considered the gold standard for empirical ionospheric models.
Victoriya V. Forsythe +5 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source