Results 41 to 50 of about 700,935 (209)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

electron density

open access: yes, 2014
Citation: 'electron density' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.E01986 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Molecular Electron Density Theory: A Modern View of Reactivity in Organic Chemistry

open access: yesMolecules, 2016
A new theory for the study of the reactivity in Organic Chemistry, named Molecular Electron Density Theory (MEDT), is proposed herein. MEDT is based on the idea that while the electron density distribution at the ground state is responsible for physical ...
Luis R. Domingo
doaj   +1 more source

An artificial neural network for analysis of ionograms obtained by ionosonde at the Ukrainian Antarctic Akademik Vernadsky station

open access: yesУкраїнський антарктичний журнал, 2020
The article presents the developed artificial neural network for F2 ionosphere layer traces scaling on ionograms obtained using the IPS-42 ionosonde installed at the Ukrainian Antarctic Akademik Vernadsky station.
O. Bogomaz   +4 more
doaj   +1 more source

Modeling of the cold electron plasma density for radiation belt physics

open access: yesFrontiers in Astronomy and Space Sciences, 2023
This review focusses strictly on existing plasma density models, including ionospheric source models, empirical density models, physics-based and machine-learning density models.
J.-F. Ripoll   +12 more
doaj   +1 more source

Electron Densities, Momentum Densities, and Density Matrices

open access: yesZeitschrift für Naturforschung A, 1993
Abstract Relationships among electron coordinate-space and momentum densities and the one-electron charge density matrix or Wigner function are examined. A knowledge of either or both densities places constraints on possible density matrices.
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Uppsala Electron-Density Server [PDF]

open access: yesActa Crystallographica Section D Biological Crystallography, 2004
The Uppsala Electron Density Server (EDS; http://eds.bmc.uu.se/) is a web-based facility that provides access to electron-density maps and statistics concerning the fit of crystal structures and their maps. Maps are available for approximately 87% of the crystallographic Protein Data Bank (PDB) entries for which structure factors have been deposited ...
Gerard J, Kleywegt   +5 more
openaire   +2 more sources

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