Results 71 to 80 of about 6,093,819 (293)

Control of tunable, monoenergetic laser-plasma-accelerated electron beams using a shock-induced density downramp injector

Physical Review Accelerators and Beams, 2017
Control of the properties of laser-plasma-accelerated electron beams that were injected along a shock-induced density downramp through precision tailoring of the density profile was demonstrated using a 1.8 J, 45 fs laser interacting with a mm-scale gas ...
K. K. Swanson, H.-E. Tsai, S. K. Barber, R. Lehe, H.-S. Mao, S. Steinke, J. van Tilborg, K. Nakamura, C. G. R. Geddes, C. B. Schroeder, E. Esarey, W. P. Leemans   +11 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Laser radiation pressure proton acceleration in gaseous target

Matter and Radiation at Extremes, 2017
An analytical model for hole boring proton acceleration by a circularly-polarized CO2 laser pulse in a gas jet is developed. The plasma density profile near the density peak is taken to be rectangular, with inner region thickness l around a laser ...
V.K. Tripathi, Tung-Chang Liu, Xi Shao
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Suppression of microbunching instability via a transverse gradient undulator

New Journal of Physics, 2015
The microbunching instability in the linear accelerator (linac) of a free-electron laser facility has always been a problem that degrades the electron beam quality.
Chao Feng, Dazhang Huang, Haixiao Deng, Qiang Gu, Zhentang Zhao   +4 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Investigation of transient transport dynamics induced by compact torus injection in the EAST tokamak

Nuclear Fusion
The rapid increase in plasma core electron temperature triggered by cold plasma injection has long been recognized as compelling evidence of nonlocal transport.
Zhihao Zhao, Chengming Qu, Chu Zhou, Yang Ye, Fubin Zhong, Mingsheng Tan, Xiaopeng Wang, Jin Zhang, Erfei Wang, Lishi Wang, Weifeng Liu, Kaibo Nan, Tao Zhang, Hailin Zhao, Meibin Qi, Defeng Kong, Shoubiao Zhang, Jinlin Xie, Chijin Xiao   +18 more
doaj   +1 more source

Longitudinal electron beam and free electron laser microbunch measurements using off-phase rf acceleration

Physical Review Special Topics. Accelerators and Beams, 2000
Magnetic dispersion followed by off-phase rf acceleration and an energy spectrometer were used to measure the longitudinal density profile of bunched relativistic electron beams with a resolution approaching 100 fs.
Kenneth N. Ricci, Todd I. Smith
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Density profile transition and high-energy electron transport in a magnetically expanding radio frequency plasma [PDF]

The density profile transition and high-energy electron transport in a magnetically expanding radio frequency (RF) plasma were investigated using particle-in-cell and Monte Carlo collision techniques, where both the plasma source and the diffusion region
Emoto, Kazuma, Takahashi, Kazunori, Takao, Yoshinori   +2 more
core   +1 more source