Results 21 to 30 of about 776,437 (281)

Imaging Molecular Structure through Femtosecond Photoelectron Diffraction on Aligned and Oriented Gas-Phase Molecules [PDF]

, 2014
This paper gives an account of our progress towards performing femtosecond time-resolved photoelectron diffraction on gas-phase molecules in a pump-probe setup combining optical lasers and an X-ray Free-Electron Laser.
Adolph, M., Anielski, D., Aquila, A., Bari, S., Boll, R., Bomme, C., Bostedt, C., Bozek, J. D., Chapman, H. N., Christensen, L., Coffee, R., Coppola, N., De, S., Decleva, P., Epp, S. W., Erk, B., Filsinger, F., Foucar, L., Gorkhover, T., Gumprecht, L., Hoemke, A., Holmegaard, L., Johnsson, P., Kienitz, J. S., Kierspel, T., Krasniqi, F., Kuehnel, K. -U., Kuepper, J., Maurer, J., Messerschmidt, M., Moshammer, R., Mueller, Nele L. M., Rolles, D., Rouzee, A., Rudek, B., Rudenko, A., Savelyev, E., Schlichting, I., Schmidt, C., Scholz, F., Schorb, S., Schulz, J., Seltmann, J., Stapelfeldt, H., Stener, M., Stern, S., Techert, S., Thogersen, J, Trippel, S., Ullrich, J., Viefhaus, J., Vrakking, M   +51 more
core   +3 more sources

Electron Backscatter Diffraction In The Sem: Is Electron Diffraction In The Tem Obsolete?

Microscopy and Microanalysis, 1997
Abstract The technique of electron backscatter diffraction (EBSD) in the scanning electron microscope is currently finding a large number of important applications in materials science. The patterns formed through EBSD were first studied over 40 years ago.
Raymond P. Goehner, Joseph R. Michael, M. E. Schlienger   +2 more
openaire   +2 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Measuring the Orbital Angular Momentum of Electron Beams

, 2014
The recent demonstration of electron vortex beams has opened up the new possibility of studying orbital angular momentum (OAM) in the interaction between electron beams and matter.
Béché, Armand, Clark, Laura, Guzzinati, Giulio, Verbeeck, Jo   +3 more
core   +1 more source

Texture, twinning and metastable "tetragonal" phase in ultrathin films of HfO₂ on a Si substrate [PDF]

, 2009
Thin HfO₂ films grown on the lightly oxidised surface of (100) Si wafers have been examined using dark-field transmission electron microscopy and selected area electron diffraction in plan view.
A. J. Craven, D. W. McComb, I. MacLaren, M. MacKenzie, S. De Gendt, T. Ras, Zhao   +6 more
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Application of Electron Diffraction to Biological Electron Microscopy

Biophysical Journal, 1969
Three methods by which electron diffraction may be applied to problems in electron microscopy are discussed from a fundamental point of view, and experimental applications with biological specimens are demonstrated for each case. It is shown that wide-angle electron diffraction provides valuable information for evaluating specimen damage that can occur
Glaeser, Robert M., Thomas, Gareth.
openaire   +4 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Electron Diffraction in the Electron Microscope [PDF]

, 1975
Electron diffraction patterns are routinely obtained in the electron microscope and are used to gain quantitative information on the following.
openaire   +2 more sources

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source