Results 51 to 60 of about 4,274,938 (365)

Electron Backscatter Diffraction In The Sem: Is Electron Diffraction In The Tem Obsolete?

Microscopy and Microanalysis, 1997
Abstract The technique of electron backscatter diffraction (EBSD) in the scanning electron microscope is currently finding a large number of important applications in materials science. The patterns formed through EBSD were first studied over 40 years ago.
Raymond P. Goehner, Joseph R. Michael, M. E. Schlienger   +2 more
openaire   +2 more sources

High-throughput continuous rotation electron diffraction data acquisition via software automation

Journal of Applied Crystallography, 2018
A semi-automated routine for continuous rotation electron diffraction has been developed, enabling high-throughput data collection. Serial electron crystallography combined with a deep convolutional network are used to screen for suitable crystals.
M. Cichocka, J. Ångström, Bin Wang, X. Zou, S. Smeets   +4 more
semanticscholar   +1 more source

Imaging an aligned polyatomic molecule with laser-induced electron diffraction [PDF]

Nature Communications, 2015
Laser-induced electron diffraction is an evolving tabletop method that aims to image ultrafast structural changes in gas-phase polyatomic molecules with sub-Ångström spatial and femtosecond temporal resolutions.

semanticscholar   +1 more source

Femtosecond gas-phase mega-electron-volt ultrafast electron diffraction

Structural Dynamics, 2019
The development of ultrafast gas electron diffraction with nonrelativistic electrons has enabled the determination of molecular structures with atomic spatial resolution.
X. Shen, J. P. F. Nunes, J. Yang, R. K. Jobe, R. K. Li, Ming-Fu Lin, B. Moore, M. Niebuhr, S. P. Weathersby, T. J. A. Wolf, C. Yoneda, Markus Guehr, Martin Centurion, X. J. Wang   +13 more
doaj   +1 more source

The Transformative Effect of Electron Diffraction [PDF]

Structural Dynamics
Crystal structures are critical to unambiguously determine a compound’s identity, absolute configuration, molecular connectivity and crystal form, as well as whether polymorphs coexist or how the solid-state structure may explain a compound’s behavior ...
Pierre Le Magueres, Joseph D Ferrara, Robert Bücker   +2 more
doaj   +1 more source

Imaging Molecular Structure through Femtosecond Photoelectron Diffraction on Aligned and Oriented Gas-Phase Molecules [PDF]

, 2014
This paper gives an account of our progress towards performing femtosecond time-resolved photoelectron diffraction on gas-phase molecules in a pump-probe setup combining optical lasers and an X-ray Free-Electron Laser.
Adolph, M., Anielski, D., Aquila, A., Bari, S., Boll, R., Bomme, C., Bostedt, C., Bozek, J. D., Chapman, H. N., Christensen, L., Coffee, R., Coppola, N., De, S., Decleva, P., Epp, S. W., Erk, B., Filsinger, F., Foucar, L., Gorkhover, T., Gumprecht, L., Hoemke, A., Holmegaard, L., Johnsson, P., Kienitz, J. S., Kierspel, T., Krasniqi, F., Kuehnel, K. -U., Kuepper, J., Maurer, J., Messerschmidt, M., Moshammer, R., Mueller, Nele L. M., Rolles, D., Rouzee, A., Rudek, B., Rudenko, A., Savelyev, E., Schlichting, I., Schmidt, C., Scholz, F., Schorb, S., Schulz, J., Seltmann, J., Stapelfeldt, H., Stener, M., Stern, S., Techert, S., Thogersen, J, Trippel, S., Ullrich, J., Viefhaus, J., Vrakking, M   +51 more
core   +3 more sources

Machining protein microcrystals for structure determination by electron diffraction

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Electron cryomicroscopy and diffraction are increasingly powerful methods for the analysis of biological structures at near-atomic resolution.
Helen M. E. Duyvesteyn, A. Kotecha, H. Ginn, Corey W. Hecksel, E. Beale, F. De Haas, G. Evans, Peijun Zhang, W. Chiu, D. Stuart   +9 more
semanticscholar   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Measuring the Orbital Angular Momentum of Electron Beams

, 2014
The recent demonstration of electron vortex beams has opened up the new possibility of studying orbital angular momentum (OAM) in the interaction between electron beams and matter.
Béché, Armand, Clark, Laura, Guzzinati, Giulio, Verbeeck, Jo   +3 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source