Results 21 to 30 of about 767,931 (314)

Chondrogenic potential of canine articular cartilage derived cells (cACCs)

open access: yesOpen Life Sciences, 2016
In the present paper, the potential of canine articular cartilage-derived cells (cACCs) for chondrogenic differentiation was evaluated. The effectiveness of cACCs’ lineage commitment was analyzed after 14 days of culture in chondorgenic and non ...
Nowak Urszula   +3 more
doaj   +1 more source

Interleukin-27 promotes autophagy in human serum-induced primary macrophages via an mTOR- and LC3-independent pathway

open access: yesScientific Reports, 2021
Interleukin-27 (IL-27) is a cytokine that suppresses human immunodeficiency virus (HIV)-1 infection in macrophages and is considered as an immunotherapeutic reagent for infectious diseases.
Sylvain Laverdure   +7 more
doaj   +1 more source

A Simplified Electron Microscope [PDF]

open access: yesPhysical Review, 1942
An electron microscope has been constructed to test a number of new methods of obtaining photographs. The aim has been to obtain in as simple a manner as possible both as regards operation and construction a resolving power in the range of the greatest present usefulness of electron microscopy (say ten times better than light microscopy), and to ...
Bachman, C. H., Ramo, Simon
openaire   +4 more sources

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

open access: yesFEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao   +4 more
wiley   +1 more source

Estimation of Complement Components (C3 and C4) and hs-CRP Level in Kidney Failure Patients

open access: yesPolytechnic, 2019
Several kidney diseases associated with complement activation. Complement activation occurs in progressive chronic kidney disease and may contribute to the chronic inflammation that is characteristically found in the kidney.
Zaid N. Elia, Nisreen W. Mustafa
doaj   +1 more source

Electron microscope studies [PDF]

open access: yes, 1991
This year our laboratory has continued to make progress in the design of electron-optical systems, in the study of structure-function relationships of large multi-subunit proteins, in the development of new image processing software and in achieving a workable sub-angstrom STEM.
Crewe, A.V., Kapp, O.H.
openaire   +5 more sources

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy