Results 31 to 40 of about 767,931 (314)

Correlative light-electron microscopy methods to characterize the ultrastructural features of the replicative and dormant liver stages of Plasmodium parasites

Malaria Journal
Background The infection of the liver by Plasmodium parasites is an obligatory step leading to malaria disease. Following hepatocyte invasion, parasites differentiate into replicative liver stage schizonts and, in the case of Plasmodium species causing ...
Gabriel Mitchell, Laura Torres, Matthew E. Fishbaugher, Melanie Lam, Vorada Chuenchob, Reena Zalpuri, Shreya Ramasubban, Caitlin N. Baxter, Erika L. Flannery, Anke Harupa, Sebastian A. Mikolajczak, Danielle M. Jorgens   +11 more
doaj   +1 more source

Designs for a quantum electron microscope

Ultramicroscopy, 2016
One of the astounding consequences of quantum mechanics is that it allows the detection of a target using an incident probe, with only a low probability of interaction of the probe and the target. This 'quantum weirdness' could be applied in the field of electron microscopy to generate images of beam-sensitive specimens with substantially reduced ...
Kruit, P., Hammer, J., Thomas, S., Weber, P., Klopfer, B., Kohstall, C., Juffmann, T., Kasevich, M.A., Hommelhoff, P., Hobbs, Richard, Kim, Chungsoo, Yang, Y., Manfrinato, Vitor Riseti, Berggren, Karl K   +13 more
openaire   +6 more sources

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Progesterone induced blocking factor in health and disease

Exploration of Immunology, 2021
The foetus expressing paternal antigens ought to be “rejected” by the maternal immune system. However, the immunological relationship of the mother and the foetus does not follow the rules of transplantation immunology.
Julia Szekeres-Bartho
doaj   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast

eLife, 2019
Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Grant A King, Jay S Goodman, Jennifer G Schick, Keerthana Chetlapalli, Danielle M Jorgens, Kent L McDonald, Elçin Ünal   +6 more
doaj   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Altered Immune Response and Implantation Failure in Progesterone-Induced Blocking Factor-Deficient Mice

Frontiers in Immunology, 2020
Earlier data suggest that progesterone-induced blocking factor (PIBF) is involved in implantation. The present study therefore aims to investigate the consequences of functional PIBF deficiency during the peri-implantation period.
Timea Csabai, Timea Csabai, Timea Csabai, Timea Csabai, Eva Pallinger, Arpad F. Kovacs, Eva Miko, Zoltan Bognar, Zoltan Bognar, Zoltan Bognar, Zoltan Bognar, Julia Szekeres-Bartho, Julia Szekeres-Bartho, Julia Szekeres-Bartho, Julia Szekeres-Bartho   +14 more
doaj   +1 more source

Elasticity of Diametrically Compressed Microfabricated Woodpile Lattices

Advanced Engineering Materials, EarlyView.
Modulus–porosity relationship is derived for woodpile lattices with struts under diametrical compression. The formula presented here that Young's modulus is proportional to the square of the volume fraction E˜ρ2$E \sim \left(\rho\right)^{2}$ is shown to be consistent with computations and laboratory experiments on 3D‐printed samples.
Faezeh Shalchy, Atul Bhaskar
wiley   +1 more source

Descriptions of diplostomid metacercariae (Digenea: Diplostomidae) from freshwater fishes in the Tshwane area

Onderstepoort Journal of Veterinary Research, 2013
The metacercarial (larval) stages of diplostomid digeneans are known to inhabit freshwater fish, causing tissue damage in the process. Due to their widespread diversity, little is known about their life cycle. The classification of these parasitic stages
Esmey B.E. Moema, Pieter H. King, Johnny N. Rakgole, Chantélle Baker   +3 more
doaj   +1 more source