Results 81 to 90 of about 6,081,547 (327)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Laser phase plate for transmission electron microscopy

open access: yesNature Methods, 2019
Transmission electron microscopy (TEM) of rapidly frozen biological specimens, or cryo-EM, would benefit from the development of a phase plate for in-focus phase contrast imaging.
O. Schwartz   +5 more
semanticscholar   +1 more source

Domain adaptive segmentation in volume electron microscopy imaging [PDF]

open access: yes, 2018
In the last years, automated segmentation has become a necessary tool for volume electron microscopy (EM) imaging. So far, the best performing techniques have been largely based on fully supervised encoder-decoder CNNs, requiring a substantial amount of ...
Hennies, Julian   +4 more
core   +1 more source

Biomass derived mesoporous carbon monoliths via an evaporation-induced self-assembly [PDF]

open access: yes, 2013
Evaporation-induced self-assembly has been applied in the synthesis of crack-free mesoporous carbon monolith with good mechanical stability using a waste plant material as carbon precursor and triblock copolymer F127 as template.
Elaigwu, Sunday E., Greenway, Gillian M.
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Wavelength-Dispersive Micro X-Ray Fluorescence (WDμXRF) Analysis with the microprobe [PDF]

open access: yesEPJ Web of Conferences
An Electron Probe Microanalyser (EPMA) determines the element distribution by detection of the electron beam excited characteristic X-rays using wavelength-dispersive spectrometers (WDS).
Nissen Jörg, Berger Dirk
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Developments, applications, and prospects of cryo‐electron microscopy

open access: yesProtein Science, 2019
Cryo‐electron microscopy (cryo‐EM) is a structural biological method that is used to determine the 3D structures of biomacromolecules. After years of development, cryo‐EM has made great achievements, which has led to a revolution in structural biology ...
Benjin Xu, Liu Ling
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

In Situ Transmission Electron Microscopy on Energy‐Related Catalysis

open access: yesAdvanced Energy Materials, 2019
Energy‐related catalytic reactions have been extensively investigated in past years in order to efficiently utilize clean and environmentally benign energy sources.
Sooyeon Hwang   +3 more
semanticscholar   +1 more source

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